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Kutikhin, Anton G.

Genomics of Pattern Recognition Receptors Applications in Oncology and Cardiovascular Diseases / [electronic resource] : by Anton G. Kutikhin, Arseniy E. Yuzhalin. - XI, 185 p. 2 illus., 1 illus. in color. online resource.

The Biology of Toll-like Receptors and NOD-like Receptors: Toggles of Inflammation -- Pattern Recognition Receptors, Gene Polymorphisms, and Cancer: A Double-Edged Sword -- Structural Genomic Variation in Toll-Like Receptor 4 and Cancer -- Structural Genomic Variation in Other Toll-like Receptors and Cancer -- Structural Genomic Variation in Toll-Like Receptor Signaling Pathway and Cancer -- Structural Genomic Variation in Toll-like Receptor Pathway and Prostate Cancer -- Structural Genomic Variation in NOD-Like Receptors and Cancer -- Structural Genomic Variation in Pattern Recognition Receptors and Cardiovascular Diseases -- Hot Spots In the Field: Where Should We Go.

This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.

9783034806886


Life sciences.
Oncology.
Human genetics.
Immunology.
Cardiology.
Cell receptors.
Life Sciences.
Receptors.
Immunology.
Cancer Research.
Human Genetics.
Oncology.
Cardiology.

QH345 QD415-436

572.696

Languages: 
English |