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ABC transporters and multidrug resistance / edited by Ahcene Boumendjel, Jean Boutonnat, Jacques Robert. - Hoboken, N.J : Wiley, 2009. - xiii, 459 p. : ill. ; 25 cm. - Wiley series in drug discovery and development .

Includes bibliographical references and index.

The P-glycoprotein 170 : just a multidrug resistance protein or a protean molecule? / Fabienne Grandjean-Forestier ... [et al.] -- Multidrug resistance-associated protein (MRP/ABCC proteins) / Mylene Honorat, Charles Dumontet, and Lea Payen -- ABCG2 : a new challenge in cancer drug resistance / Orsolya Polgar ... [et al.] -- Expression, detection, and implication of ABC proteins in acute myeloblastic leukemia / Ollivier Legrand, Ruo-Ping Tang, and Jean-Pierre Marie -- ABC proteins and oncology: expression, detection, and implication of ABC proteins in solid tumors / Jean Fran�cois Bernaudin ... [et al.] -- ABC transporters and resistance to antibiotics / Serge Michalet and Marie-Genevi�eve Dijoux-Franca -- ABC proteins involved in protozoan parasite resistance / Bruno Pradines -- Reversal agents for P-glycoprotein-mediated multidrug resistance / Hamid Morjani and Claudie Madoulet -- Reversal agents of multidrug resistance mediated by multidrug resistance-assocated proteins (MRPs) / Ahc�ene Boumendjel, Anne Florin, and Jean Boutonnat -- Reversal agents for breast cancer resistance protein (BCRP)-mediated multidrug resistance / Jean Boutonnat, Anne Florin, and Jean Boutonnat -- Strategies to overcome drug resistance in acute and chronic leukemias / Eric Solary, Vincent Ribrag, and St�ephanie de Botton -- Multidrug resistance reversal in solid tumors / Tatiana Bogush and Jacques Robert -- ABC superfamily transporters at the human blood-brain barrier / Jean-Michel Scherrmann -- The role of ABC transporters at the intestinal barrier / Roos L. Oostendorp, Jos H. Beijnen, and Jan H.M. Schellens -- Genetic polymorphisms in ABC transporters / Leslie W. Chinn and Deanna L. Kroetz.

9780470227343 (cloth)


ATP-binding cassette transporters.
Drug resistance in cancer cells.
Multidrug Resistance-Associated Proteins.
Drug Resistance, Multiple.
Neoplasms--drug therapy.

572.696 / A347

Languages: 
English |