ADMET for medicinal chemists : a practical guide /
Absorption, distribution, metabolism, excretion, toxicity for medical chemists
edited by Katya Tsaioun, Steven A. Kates.
- Hoboken, N.J. : Wiley, 2011.
- xx, 498 p. : 25 cm.
Includes bibliographical references and index.
In silico ADME/tox predictions / David Lagorce ... [et al.] -- Absorption and physicochemical properties of the NCE / Jon Selbo and Po-Chang Chiang -- ADME / Martin E. Dowty ... [et al.] -- Pharmacokinetics for medicinal chemists / Leo Kirkovsky and Anup Zutshi -- Cardiac toxicity / Ralf Kettenhofen and Silke Schwengberg -- Genetic toxicity : in vitro approaches for medicinal chemists / Richard M. Walmsley and David Elder -- Hepatic toxicity / Jinghai James Xu and Keith Hoffmaster -- In vivo toxicological considerations / John P. Devine Jr. --Pre-clinical candidate nomination and development / Nils Bergenhem -- Fragment-based drug design : considerations for good ADME properties / Haitao Ji.
9780470484074 (cloth)
Drugs--Testing--Juvenile literature. Drug Design. Drug Toxicity. Pharmaceutical Preparations--chemistry. Pharmacokinetics.