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High-throughput analysis in the pharmaceutical industry / edited by Perry G. Wang. - Boca Raton, FL : CRC Press, 2009. - 413 p. : ill. ; 26 cm. - Critical reviews in combinatorial chemistry .

Errata slip inserted.

Includes bibliographical references and index.

High-throughput sample preparation techniques and their application to bioanalytical protocols and purification of combinatorial libraries / Krishna Kallury -- Online sample extraction coupled with multiplexing strategy to improve throughput / Katty X. Wan -- Optimizing LC/MS equipment to increase throughput in pharmaceutical analysis / Michael G. Frank and Douglas E. McIntyre -- Throughput improvement of bioanalytical LC/MS/MS by sharing detector between HPLC systems / Min Shuan Chang and Tawakol El-Shourbagy -- High-throughput strategies for metabolite identification in drug discovery / Patrick J. Rudewicz, Qin Yue, and Young Shin -- Utilizing microparallel liquid chromatography for high-throughput analyses in the pharmaceutical industry / Sergio A. Guazzotti -- Strategies and techniques for higher throughput ADME/PK assays / Walter Korfmacher -- High-throughput analysis in drug metabolism during early drug discovery / Yau Yi Lau -- High-throughput analysis in the support of process chemistry and formulation research and development in the pharmaceutical industry / Zhong Li -- Online solid phase extraction LC/MS/MS for high-throughput bioanalytical analysis / Dong Wei and Liyu Yang -- Applications of high-throughput analysis in therapeutic drug monitoring / Quanyun A. Xu and Timothy L. Madden -- High-throughput quantitative pharmaceutical analysis in drug metabolism and pharmacokinetics using liquid chromatography-mass spectrometry / Xiaohui Xu -- Designing high-throughput HPLC assays for small and biological molecules / Roger K. Gilpin and Wanlong Zhou -- Advances in capillary and nano HPLC technology for drug discovery and development / Frank J. Yang and Richard Xu -- High-throughput analysis of complex protein mixtures by mass spectrometry / Kojo S.J. Elenitoba-Johnson.

9781420059533 (hardcover : alk. paper) 142005953X (hardcover : alk. paper)


High throughput screening (Drug development)
Combinatorial chemistry.
Combinatorial Chemistry Techniques--methods.
Drug Design.
Pharmaceutical Preparations--analysis.
Technology, Pharmaceutical--methods.

RS419.5 / .H536 2009

615.19 / H536

Languages: 
English |