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How do we best employ animal models for type 1 diabetes and multiple sclerosis? /
edited by Matthias von Herrath and Mark Atkinson.
- Boston, Mass. : Blackwell Pub. on behalf of the New York Academy of Sciences, 2007.
- xii, 220 p. : ill. (some col.) ; 23 cm.
- Annals of the New York Academy of Sciences, 1078 0077-8923 ; .
Includes bibliographical references and index.
Are insights gained from NOD mice sufficient to guide clinical translation? another inconvenient truth / by Bart O. Roep -- Building different mouse models for human MS / by Estelle Bettelli -- Autoimmunity and [beta] cell regeneration in mouse and human type 1 diabetes: the peace is not enough / by Vitaly Ablamunits ... [et al.] -- Diabetes research in jeopardy: the extinction of clinical diabetes researchers / by Aldo A. Rossini and Dale L. Greiner -- The virtual NOD mouse: applying predictive biosimulation to research in type 1 diabetes / by Yanan Zheng ... [et al.] -- Dosing and timing effects of anti-CD40L therapy: predictions from a mathematical model of type 1 diabetes / by Kapil G. Gadkar ... [et al.] -- Autoreactive T cells in a partially humanized murine model of T1D / by John A Gebe ... [et al.] -- Humanized NOD/LtSz-scid IL2 receptor common gamma chain knockout mice in diabetes research / by Leonard D. Shultz ... [et al.] -- Development of new-generation HU-PBMC-NOD/SCID mice to study human islet alloreactivity / by Marie King ... [et al.] -- Resistance to the induction of mixed chimerism in spontaneously diabetic NOD mice depends on the CD40/CD154 pathway and donor MHC disparity / by Bin Luo ... [et al.] -- "Humanized" HLA transgenic NOD mice to identify pancreatic [beta] cell autoantigens of potential clinical relevance to type 1 diabetes / by David V. Serreze, Michele P. Marron, and Teresa P. DiLorenzo -- A new humanized HLA transgenic mouse model of multiple sclerosis expressing class II on mouse CD4 T cells / by Ashutosh Mangalam, Moses Rodriguez, and Chella David -- The use of Idd congenic mice to identify checkpoints of peripheral tolerance to islet antigen / by Emma E. Hamilton-Williams ... [et al.] -- Refinement of the Iddm4 diabetes susceptibility locus reveals TCRV[beta]4 as a candidate gene / by Elizabeth P. Blankenhorn... [et al.] -- Cytotoxic T cell-mediated diabetes in RIP-CD80 transgenic mice: autoantigen peptide sensitivity and fine specificity / by Klaus Pechhold, Sagarika Chakrabarty, and David M. Harlan -- Coxsackievirus infections and NOD mice: relevant models of protection from, and induction of, type 1 diabetes / by Steven Tracy and Kristen M. Drescher -- Establishment of a model to examine the early events involved in the development of virus-induced demyelinating lesions / by Kristen M. Drescher and Steven Tracy -- Experimental autoimmune encephalomyelitis mediated by CD8+ T cells / by Qingyong Ji and Joan Goverman -- Impaired T cell receptor signaling in Foxp3+ CD4 T cells / by Bryan D. Carson and Steven F. Ziegler -- Antigen presentation in the CNS by myeloid dendritic cells drives progression of relapsing experimental autoimmune encephalomyelitis / by Stephen D. Miller... [et al.] -- Human clonal CD8 autoreactivity to an IGRP islet epitope shared between mice and men / by W.W.J. Unger ... [et al.] -- Matrix metalloproteinase-2 expression and apoptogenic activity in retinal pericytes: implications in diabetic retinopathy / by Ru Yang ... [et al.] -- Mouse models for cardiovascular complications of type 1 diabetes / by Xia Shen and Karen E. Bornfeldt.
9781573316781 (pbk. : alk. paper) 1573316784 (pbk. : alk. paper)
Diabetes--Animal models--Congresses.
Multiple sclerosis--Animal models--Congresses.
Diabetes Mellitus, Type 1.--Congresses
Disease Models, Animal--Congresses.
Multiple Sclerosis--Congresses.
RC660 / .H72 2007
616.462 / H72
Includes bibliographical references and index.
Are insights gained from NOD mice sufficient to guide clinical translation? another inconvenient truth / by Bart O. Roep -- Building different mouse models for human MS / by Estelle Bettelli -- Autoimmunity and [beta] cell regeneration in mouse and human type 1 diabetes: the peace is not enough / by Vitaly Ablamunits ... [et al.] -- Diabetes research in jeopardy: the extinction of clinical diabetes researchers / by Aldo A. Rossini and Dale L. Greiner -- The virtual NOD mouse: applying predictive biosimulation to research in type 1 diabetes / by Yanan Zheng ... [et al.] -- Dosing and timing effects of anti-CD40L therapy: predictions from a mathematical model of type 1 diabetes / by Kapil G. Gadkar ... [et al.] -- Autoreactive T cells in a partially humanized murine model of T1D / by John A Gebe ... [et al.] -- Humanized NOD/LtSz-scid IL2 receptor common gamma chain knockout mice in diabetes research / by Leonard D. Shultz ... [et al.] -- Development of new-generation HU-PBMC-NOD/SCID mice to study human islet alloreactivity / by Marie King ... [et al.] -- Resistance to the induction of mixed chimerism in spontaneously diabetic NOD mice depends on the CD40/CD154 pathway and donor MHC disparity / by Bin Luo ... [et al.] -- "Humanized" HLA transgenic NOD mice to identify pancreatic [beta] cell autoantigens of potential clinical relevance to type 1 diabetes / by David V. Serreze, Michele P. Marron, and Teresa P. DiLorenzo -- A new humanized HLA transgenic mouse model of multiple sclerosis expressing class II on mouse CD4 T cells / by Ashutosh Mangalam, Moses Rodriguez, and Chella David -- The use of Idd congenic mice to identify checkpoints of peripheral tolerance to islet antigen / by Emma E. Hamilton-Williams ... [et al.] -- Refinement of the Iddm4 diabetes susceptibility locus reveals TCRV[beta]4 as a candidate gene / by Elizabeth P. Blankenhorn... [et al.] -- Cytotoxic T cell-mediated diabetes in RIP-CD80 transgenic mice: autoantigen peptide sensitivity and fine specificity / by Klaus Pechhold, Sagarika Chakrabarty, and David M. Harlan -- Coxsackievirus infections and NOD mice: relevant models of protection from, and induction of, type 1 diabetes / by Steven Tracy and Kristen M. Drescher -- Establishment of a model to examine the early events involved in the development of virus-induced demyelinating lesions / by Kristen M. Drescher and Steven Tracy -- Experimental autoimmune encephalomyelitis mediated by CD8+ T cells / by Qingyong Ji and Joan Goverman -- Impaired T cell receptor signaling in Foxp3+ CD4 T cells / by Bryan D. Carson and Steven F. Ziegler -- Antigen presentation in the CNS by myeloid dendritic cells drives progression of relapsing experimental autoimmune encephalomyelitis / by Stephen D. Miller... [et al.] -- Human clonal CD8 autoreactivity to an IGRP islet epitope shared between mice and men / by W.W.J. Unger ... [et al.] -- Matrix metalloproteinase-2 expression and apoptogenic activity in retinal pericytes: implications in diabetic retinopathy / by Ru Yang ... [et al.] -- Mouse models for cardiovascular complications of type 1 diabetes / by Xia Shen and Karen E. Bornfeldt.
9781573316781 (pbk. : alk. paper) 1573316784 (pbk. : alk. paper)
Diabetes--Animal models--Congresses.
Multiple sclerosis--Animal models--Congresses.
Diabetes Mellitus, Type 1.--Congresses
Disease Models, Animal--Congresses.
Multiple Sclerosis--Congresses.
RC660 / .H72 2007
616.462 / H72