Principles of clinical genetics : the Massachusetts General Hospital guide to clinical cancer genetics /
Massachusetts General Hospital guide to clinical cancer genetics.
edited by Daniel C. Chung and Daniel A. Haber.
- New York : Springer, 2010.
- xi, 227 p. : ill.
Includes bibliographical references and index.
Basic principles of cancer genetics -- Principles of cancer genetic counseling and genetic testing -- Genetics of hereditary breast cancer -- Surgical management of hereditary breast and ovarian cancer -- Hereditary colon cancer: colonic polyposis syndromes -- Hereditary colon cancer: Lynch syndrome -- Hereditary pancreatic cancer -- Hereditary diffuse gastric cancer -- Familial renal cell cancers and pheochromocytomas -- Familial atypical mole melanoma (FAMM) syndrome -- Multiple endocrine neoplasia -- Pediatric malignancies: retinoblastoma and Wilms' tumor -- Neurofibromatosis and Schwannomatosis -- The HapMap project and low-penetrance cancer susceptibility alleles -- Somatic genetic alterations and implications for targeted therapies in cancer (GIST, CMI, lung cancer)