| 000 -LEADER |
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| fixed length control field |
03070nam a22004815i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20140310150232.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
100301s2010 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9781441914828 |
|
978-1-4419-1482-8 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
RB155-155.8 |
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|---|
| Classification number |
QH431 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
611.01816 |
| Edition number |
23 |
|
|---|
| Classification number |
599.935 |
| Edition number |
23 |
| 264 #1 - |
|---|
| -- |
New York, NY : |
| -- |
Springer New York, |
| -- |
2010. |
| 912 ## - |
|---|
| -- |
ZDB-2-SBL |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Wallace, Rodrick. |
| Relator term |
author. |
| 245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Title |
Gene Expression and Its Discontents |
| Medium |
[electronic resource] : |
| Remainder of title |
The Social Production of Chronic Disease / |
| Statement of responsibility, etc |
by Rodrick Wallace, Deborah Wallace. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
X, 230p. 16 illus. |
| Other physical details |
online resource. |
| 505 0# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
Models of development -- Groupoid symmetries -- Epigenetic catalysis -- Developmental disorders -- An interim perspective -- The obesity pandemic in the US -- Coronary heart disease in the US -- Cancer: a developmental perspective -- Autoimmune disorders -- Demoralization and obesity in Upper Manhattan -- Death at an early age: AIDS and related mortality in New York City -- Final thoughts -- Mathematical appendix -- References. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
A cognitive paradigm for gene expression, via the asymptotic limit theorems of information theory, allows better understanding of how embedding context affects the development of organisms. In sum, epigenetic information sources act as tunable catalysts, directing ontogeny into characteristic pathways, a perspective having important implications for epigenetic epidemiology. The authors show how environmental stressors, in a large sense, can induce a broad spectrum of developmental dysfunctions, and examine a number of pandemic chronic diseases, using U.S. data at different scales on the effects of the legacy of slavery compounded by accelerating industrial and urban decay. Developmental disorders, broadly taken, are unlikely to respond to medical interventions in the face of serious, persistent individual and community stress. In particular, drugs powerful enough to affect deleterious epigenetic programming will likely trigger side effects leading to shortened lifespan. The address of pandemic chronic disease requires significant large-scale changes in public policy and resource allocation. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Medicine. |
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| Topical term or geographic name as entry element |
Human genetics. |
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| Topical term or geographic name as entry element |
Epidemiology. |
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|---|
| Topical term or geographic name as entry element |
Bioinformatics. |
|
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| Topical term or geographic name as entry element |
Biomedicine. |
|
|---|
| Topical term or geographic name as entry element |
Human Genetics. |
|
|---|
| Topical term or geographic name as entry element |
Computational Biology/Bioinformatics. |
|
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| Topical term or geographic name as entry element |
Public Health/Gesundheitswesen. |
|
|---|
| Topical term or geographic name as entry element |
Epidemiology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Wallace, Deborah. |
| Relator term |
author. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Printed edition: |
| International Standard Book Number |
9781441914811 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-4419-1482-8 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Item type |
E-Book |
