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003 - CONTROL NUMBER IDENTIFIER |
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005 - DATE AND TIME OF LATEST TRANSACTION |
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20140310150233.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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100316s2010 xxu| s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9781441916723 |
|
978-1-4419-1672-3 |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
RC321-580 |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
612.8 |
Edition number |
23 |
264 #1 - |
-- |
New York, NY : |
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Springer New York, |
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2010. |
912 ## - |
-- |
ZDB-2-SBL |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Reichenbach, Andreas. |
Relator term |
author. |
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
Title |
Müller Cells in the Healthy and Diseased Retina |
Medium |
[electronic resource] / |
Statement of responsibility, etc |
by Andreas Reichenbach, Andreas Bringmann. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
XII, 200p. 70 illus. |
Other physical details |
online resource. |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
Introduction -- Basic properties of Müller cells -- Müller cell gliosis -- Müller cells in the healthy retina -- Retinal Development -- Müller cells as 'light cables' -- Soft Müller cells as shock absorbers and axon paths -- 'Metabolic symbiosis' -- Neurotransmitter recycling -- Retinal K+ homeostasis -- Retinal water homeostasis -- Other interactions -- Müller cells in the diseased retina -- Retinal detachment -- Diabetic retinopathy -- Macular edema -- Proliferative retinopathies -- Ischemia-reperfusion -- Hepatic retinopathy -- Retinoschisis -- Retinitis pigmentosa and support of neuronal survival -- Future directions -- Index. |
520 ## - SUMMARY, ETC. |
Summary, etc |
Müller cells make up just 0.005% of the cells in our central nervous system. They do not belong to the more esteemed family of neuronal cells but to the glia, a family of cells that until recently were seen as mere filling material between the neurons. Now, however, all that has changed. Sharing the insights of more than a quarter century of research into Müller cells, Drs. Andreas Reichenbach and Andreas Bringmann of Leipzig University make a compelling case for the central role Müller cells play. Everyone agrees that the eye is a very special and versatile sense organ, yet it has turned out in recent years that Müller cells are peculiar and multipotent glial cells. In the retina of most vertebrates and even of many mammals, Müller cells are the only type of (macro-) glial cells; thus, they are responsible for a wealth of neuron-supportive functions that, in the brain, rely upon a division of labour among astrocytes, oligodendrocytes, and ependymal cells. Even beyond such a role in the central nervous system as "model glia", Müller cells are adapted to several exciting roles in support of vision. They deliver the light stimuli to the photoreceptor cells in the inverted vertebrate retina, aid the processing of visual information, and are responsible for the homeostatic maintenance of the retinal extracellular milieu. In Müller Cells in the Healthy and Diseased Retina, aimed not just at neurobiologists but at anyone concerned with retinal degeneration, every angle of Müller cells is covered, from an introduction to their basic properties, through their roles as ‘light cables’ and ‘shock absorbers’, to the part they play in diseases and disorders of the eye. Once these have all been covered in detail, the authors move on to discuss the future direction of research into these small but potent cellular phenomena. About the Authors Dr. Andreas Reichenbach was born in 1950 in Leipzig, Germany. He studied medicine and specialized as a physiologist, working on the mammalian retina. Since 1984, he has focused his efforts – and those of a growing number of fellows in his team – on Müller cell research. He has held a professorship at Leipzig University since 1994. After studying biology, Dr. Andreas Bringmann (* 1960) worked in the field of systemic neurophysiology until he was inspired in 1996 by Andreas Reichenbach to research the most interesting cell, the Müller cell. He is now in the Department of Ophthalmology of the University of Leipzig where he is the head of the Basic Research Laboratory. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name as entry element |
Medicine. |
|
Topical term or geographic name as entry element |
Neurosciences. |
|
Topical term or geographic name as entry element |
Ophthalmology. |
|
Topical term or geographic name as entry element |
Cytology. |
|
Topical term or geographic name as entry element |
Neurobiology. |
|
Topical term or geographic name as entry element |
Biomedicine. |
|
Topical term or geographic name as entry element |
Neurosciences. |
|
Topical term or geographic name as entry element |
Ophthalmology. |
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Topical term or geographic name as entry element |
Neurobiology. |
|
Topical term or geographic name as entry element |
Cell Biology. |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Bringmann, Andreas. |
Relator term |
author. |
710 2# - ADDED ENTRY--CORPORATE NAME |
Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
773 0# - HOST ITEM ENTRY |
Title |
Springer eBooks |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Display text |
Printed edition: |
International Standard Book Number |
9781441916716 |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-4419-1672-3 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
|
Item type |
E-Book |