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005 - DATE AND TIME OF LATEST TRANSACTION |
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20140310150233.0 |
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100825s2010 xxu| s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9781441956354 |
|
978-1-4419-5635-4 |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
RE1-994 |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
617.7 |
Edition number |
23 |
264 #1 - |
-- |
New York, NY : |
-- |
Springer New York : |
-- |
Imprint: Springer, |
-- |
2010. |
912 ## - |
-- |
ZDB-2-SBL |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Lambris, John D. |
Relator term |
editor. |
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
Title |
Inflammation and Retinal Disease: Complement Biology and Pathology |
Medium |
[electronic resource] / |
Statement of responsibility, etc |
edited by John D. Lambris, Anthony P. Adamis. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
XIV, 170 p. |
Other physical details |
online resource. |
440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE |
Title |
Advances in Experimental Medicine and Biology, |
International Standard Serial Number |
0065-2598 ; |
Volume number/sequential designation |
703 |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
The Case for Complement and Inflammation in AMD: Open Questions -- The Role of Complement in AMD -- Multiple Interactions of Complement Factor H with Its Ligands in Solution: A Progress Report -- Genetic Control of Complement Activation in Humans and Age Related Macular Degeneration -- Bisretinoids of RPE Lipofuscin: Trigger for Complement Activation in Age-Related Macular Degeneration -- The Role of the Classical Complement Cascade in Synapse Loss During Development and Glaucoma -- A Role for Complement in Glaucoma? -- The ATP-Binding Cassette Transporter ABCA4: Structural and Functional Properties and Role in Retinal Disease -- Suppression of Drusen Formation by Compstatin, a Peptide Inhibitor of Complement C3 activation, on Cynomolgus Monkey with Early-Onset Macular Degeneration -- A Targeted Inhibitor of the Complement Alternative Pathway Reduces RPE Injury and Angiogenesis in Models of Age-Related Macular Degeneration -- Complement Depletion with Humanized Cobra Venom Factor in a Mouse Model of Age-Related Macular Degeneration. |
520 ## - SUMMARY, ETC. |
Summary, etc |
Numerous studies have pointed to the key role of complement in the pathogenesis of retinal disease, particularly age-related macular degeneration (AMD). Reports about new gene associations and links to other physiological pathways are emerging almost on a weekly base. Several promising clinical candidates covering a wide area of potential treatment applications are in the pipelines of both industrial and academic groups. This indicates an increasing interest in complement as a therapeutic target. In view of these exciting discoveries, scientists from around the world convened at the 1st Aegean Conferences Conference on Inflammation and Retinal Disease: Complement Biology and Pathology (June 10-17, 2007) in Crete, Greece, to discuss recent advances in this rapidly-evolving field. This volume represents a collection of topics on the functions of complement in eye diseases, pathophysiology, protein structures, and complement therapeutics discussed during the conference. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name as entry element |
Medicine. |
|
Topical term or geographic name as entry element |
Ophthalmology. |
|
Topical term or geographic name as entry element |
Medicine & Public Health. |
|
Topical term or geographic name as entry element |
Ophthalmology. |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Adamis, Anthony P. |
Relator term |
editor. |
710 2# - ADDED ENTRY--CORPORATE NAME |
Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
773 0# - HOST ITEM ENTRY |
Title |
Springer eBooks |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Display text |
Printed edition: |
International Standard Book Number |
9781441956347 |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-4419-5635-4 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
|
Item type |
E-Book |