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Environmental Factors, Genes, and the Development of Human Cancers (Record no. 17291)

000 -LEADER
fixed length control field 04456nam a22004455i 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140310150234.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 100917s2010 xxu| s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781441967527
978-1-4419-6752-7
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RC261-271
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 614.5999
Edition number 23
264 #1 -
-- New York, NY :
-- Springer New York :
-- Imprint: Springer,
-- 2010.
912 ## -
-- ZDB-2-SBL
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Roy, Deodutta.
Relator term editor.
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE
Title Environmental Factors, Genes, and the Development of Human Cancers
Medium [electronic resource] /
Statement of responsibility, etc edited by Deodutta Roy, M. Tevfik Dorak.
300 ## - PHYSICAL DESCRIPTION
Extent XIII, 300p. 39 illus., 28 illus. in color.
Other physical details online resource.
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note General Principles -- Gene–Environment Interactions, Phenotypic Changes, and Human Health -- Statistics for Testing Gene–Environment Interaction -- Clustering Studies for Identifying the Role of Environmental Factors in Aetiology of Human Cancers -- Discovering Gene–Gene and Gene–Environment Causal Interactions Using Bioinformatics Approaches -- Gene Environment Interactions and Vascular Lesions -- Epigenetic Changes in Cancer: Role of Environment -- Approaches to Identify Environmental and Epigenomic Components or Covariates of Cancer and Disease Susceptibility -- Environment and Specific Types of Cancer -- Gene–Environment Interaction and Susceptibility to Pediatric Brain Tumors -- Genetic Polymorphisms Predisposing Individuals to Breast Cancer Via Gene–Environment Interaction -- Environment, Genetic Immunology and Childhood Cancer -- Exposure to Environmental Mutagens: APC and Colorectal Carcinogenesis -- Gene–Environmental Interactions and Susceptibility to Liver Cancer -- Genetic Epidemiology of Mismatch Repair Deficiency in Ovarian Cancer -- Case Studies -- Betel Nut and Susceptibility to Cancer -- Birth Weight and Cancer Associations -- Iron Excess and Cancer.
520 ## - SUMMARY, ETC.
Summary, etc Cancer is a complex disease. Only 5-10% of human cancers are hereditary in nature. Many of us think of environmental agents when we think of carcinogens. The environment includes all that surrounds us, and environmental influences include not only chemical, physical and biological toxicants, but also diet and lifestyle. In this broadest sense, the environment contributes substantially in the development of human cancer. This book will describe how environment contributes to malignant transformation leading to profound changes in the genetic and signaling networks that control the functioning of the cell. It will critically discuss the understanding of the effects of environment on the development, progression and metastasis of cancer with current knowledge of the signaling networks that support functioning of transformed human cells. Genes and environmental factors that influence the origins of cancer are not necessarily the same as those that contribute to its progression and metastasis. Susceptibility gene variants for each specific cancer are being identified with emerging evidence of gene–environment interaction. Gene-environment interactions will be discussed through each specific cancer-based approach to address the question of how genetic variations can influence susceptibility to the individual type of cancer. It will also highlight and summarize epigenetic changes that increase the risk for susceptibility to a particular type of cancer, particularly in the presence of specific environmental factors. Thus, this book will contain chapters from the world’s experts focused on the current evidences that support the role of environment in the cancer etiology and in the growth of malignant lesions, and discuss who may be susceptible to environmental influences.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
Topical term or geographic name as entry element Oncology.
Topical term or geographic name as entry element Toxicology.
Topical term or geographic name as entry element Environmental Medicine.
Topical term or geographic name as entry element Biomedicine.
Topical term or geographic name as entry element Cancer Research.
Topical term or geographic name as entry element Environmental Health.
Topical term or geographic name as entry element Pharmacology/Toxicology.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Dorak, M. Tevfik.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9781441967510
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-1-4419-6752-7
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Item type E-Book
Copies
Price effective from Permanent location Date last seen Not for loan Date acquired Source of classification or shelving scheme Koha item type Damaged status Lost status Withdrawn status Current location Full call number
2014-04-04AUM Main Library2014-04-04 2014-04-04 E-Book   AUM Main Library614.5999
Languages: 
English |
العربية