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| fixed length control field |
02904nam a22003855i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20140310150234.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
110111s2010 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9781441970022 |
|
978-1-4419-7002-2 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
R-RZ |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
610 |
| Edition number |
23 |
| 264 #1 - |
|---|
| -- |
Boston, MA : |
| -- |
Springer US, |
| -- |
2010. |
| 912 ## - |
|---|
| -- |
ZDB-2-SBL |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Tavernarakis, Nektarios. |
| Relator term |
editor. |
| 245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Title |
Protein Metabolism and Homeostasis in Aging |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc |
edited by Nektarios Tavernarakis. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XXII, 248p. 34 illus., 4 illus. in color. |
| Other physical details |
online resource. |
| 440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE |
|---|
| Title |
Advances in Experimental Medicine and Biology, |
| International Standard Serial Number |
0065-2598 ; |
| Volume number/sequential designation |
694 |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Synthesis, Modification and Turnover of Proteins during Aging -- Regulation of mRNA Translation as a Conserved Mechanism of Longevity Control -- Protein Synthesis and the Antagonistic Pleiotropy Hypothesis of Aging -- Proteasome Function Determines Cellular Homeostasis and the Rate of Aging -- Autophagy and Longevity: Lessons from C. elegans -- Autophagy and Aging: Lessons from Progeria Models -- Regulation of Protein Turnover by Longevity Pathways -- Protein Metabolism and Lifespan in Caenorhabditis elegans -- Mitochondrial Protein Quality Control Systems in Aging and Disease -- p38MAPK in the Senescence of Human and Murine Fibroblasts -- Protein Homeostasis in Models of Aging and Age-Related Conformational Disease -- Roles for SUMO Modification during Senescence -- Post-Translational Modification of Cellular Proteins by Ubiquitin and Ubiquitin-Like Molecules: Role in Cellular Senescence and Aging -- Sensory Influence on Homeostasis and Lifespan: Molecules and Circuits -- Regulation of Muscle Atrophy in Aging and Disease -- Confronting Cellular Heterogeneity in Studies of Protein Metabolism and Homeostasis in Aging Research. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
The focus of this book is on the role of protein metabolism and homeostasis in aging. An overview is provided of the current knowledge in the area, including protein synthesis, accuracy and repair, post‑translational modifications, degradation and turnover, and how they define and influence aging. The chapters mainly focus on well‑characterized factors and pathways, but new areas are also presented, where associations with aging are just being elucidated by current experimental data. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Medicine. |
|
|---|
| Topical term or geographic name as entry element |
Biomedicine. |
|
|---|
| Topical term or geographic name as entry element |
Biomedicine general. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Printed edition: |
| International Standard Book Number |
9781441970015 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-4419-7002-2 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Item type |
E-Book |
