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003 - CONTROL NUMBER IDENTIFIER |
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005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20140310150234.0 |
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fixed length control field |
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110713s2010 xxu| s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9781441978233 |
|
978-1-4419-7823-3 |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
R-RZ |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
610 |
Edition number |
23 |
264 #1 - |
-- |
New York, NY : |
-- |
Springer US, |
-- |
2010. |
912 ## - |
-- |
ZDB-2-SBL |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Großhans, Helge. |
Relator term |
editor. |
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
Title |
Regulation of microRNAs |
Medium |
[electronic resource] / |
Statement of responsibility, etc |
edited by Helge Großhans. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
XVI, 160p. 35 illus., 6 illus. in color. |
Other physical details |
online resource. |
440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE |
Title |
Advances in Experimental Medicine and Biology, |
International Standard Serial Number |
0065-2598 ; |
Volume number/sequential designation |
700 |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
microRNA Biogenesis and Function -- Regulation of pri-miRNA Processing Through Smads -- Stimulation of pri-miR-18a Processing by hnRNP A1 -- KSRP Promotes the Maturation of a Group of miRNA Precuresors -- Hormonal Repression of miRNA Biosynthesis Through a Nuclear Steroid Hormone Receptor -- Autoregulatory Mechanisms Controlling the Microprocessor -- Regulation of pre-miRNA Processing -- The Effect of RNA Editing and ADARs on miRNA Biogenesis and Function -- miRNAs Need a Trim -- Properties of the Regulatory RNA-Binding Protein HuR and its Role in Controlling miRNA Repression -- Turnover of Mature miRNAs and siRNAs in Plants and Algae -- MicroRNases and the Regulated Degradation of Mature Animal miRNAs. |
520 ## - SUMMARY, ETC. |
Summary, etc |
Given this pervasiveness and importance of miRNA-mediated gene regulation, it should come as little surprise that miRNAs themselves are also highly regulated. However, the recent explosion of knowledge on this topic has been remarkable, providing a primary motivation for publication of this book. As miRNAs are transcribed by RNA polymerase II, the enzyme that also generates mRNAs, it was perhaps not unexpected that miRNA transcription would be subject to regulation, and we have willfully mitted this aspect from this monograph. However, what has been unexpected is the extent of post-transcriptional regulation of miRNAs that is illustrated in this book. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name as entry element |
Medicine. |
|
Topical term or geographic name as entry element |
Human genetics. |
|
Topical term or geographic name as entry element |
Biomedicine. |
|
Topical term or geographic name as entry element |
Biomedicine general. |
|
Topical term or geographic name as entry element |
Human Genetics. |
710 2# - ADDED ENTRY--CORPORATE NAME |
Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
773 0# - HOST ITEM ENTRY |
Title |
Springer eBooks |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Display text |
Printed edition: |
International Standard Book Number |
9781441978226 |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-4419-7823-3 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
|
Item type |
E-Book |