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OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20140310150234.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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110106s2011 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9781441979643 |
|
978-1-4419-7964-3 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
QH301-705 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
570 |
| Edition number |
23 |
| 264 #1 - |
|---|
| -- |
New York, NY : |
| -- |
Springer New York : |
| -- |
Imprint: Springer, |
| -- |
2011. |
| 912 ## - |
|---|
| -- |
ZDB-2-SBL |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Dubitzky, Werner. |
| Relator term |
editor. |
| 245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Title |
Understanding the Dynamics of Biological Systems |
| Medium |
[electronic resource] : |
| Remainder of title |
Lessons Learned from Integrative Systems Biology / |
| Statement of responsibility, etc |
edited by Werner Dubitzky, Jennifer Southgate, Hendrik Fuß. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XIV, 238p. 120 illus. |
| Other physical details |
online resource. |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Preface -- Effects of Protein Quality Control Machinery on Protein Homeostasis -- Metabolic Network Dynamics: Properties and Principles -- A Deterministic, Mathematical Model for Hormonal Control of the Menstrual Cycle -- Modelling Transport Processes and their Implications for Chemical Disposition and Action -- Systems Biology of Tuberculosis: Insights for Drug Discovery -- Qualitative Analysis of Genetic Regulatory Networks in Bacteria -- Modelling Antibiotic Resistance in Bacterial Colonies Using Agent-Based Approach -- Modelling the Spatial Pattern Forming Modules in Mitotic Spindle Assembly -- Cell-Centred Modelling of Tissue Behaviour -- Interaction-Based Simulations for Integrative Spatial Systems Biology -- Glossary -- Index. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
Systems biology has risen as a direct result of the limitation of conventional (reductionistic) biology to understand complex phenomena emerging as a result of dynamic and multiscale biological interactions. By applying mathematical and computational models, systems biologists integrate the elementary processes into a coherent description that allows them to predict and characterize the systems-level properties and behavior of complex biological phenomena. As the field of systems biology matures, we are beginning to see practical answers to real biological problems. It is timely to step back and review the insight obtained from a systems biology approach by presenting an overview of current research. The book encompasses the key disciplines of biology, mathematics, and information technology that contribute to systems biology. It introduces some of the main methods and techniques of systems biology and assesses their contributions based on case studies. The biological phenomena investigated include tissue organization, hormonal control, bacterial stress response, tumor growth and cellular metabolism. Each chapter serves simultaneously as design blueprint, user guide, research agenda and communication platform. The book is targeted at an interdisciplinary audience consisting of students, teachers, researchers, developers, and practitioners in life science, mathematics, computer science and cognate areas. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Life sciences. |
|
|---|
| Topical term or geographic name as entry element |
Bioinformatics. |
|
|---|
| Topical term or geographic name as entry element |
Biological models. |
|
|---|
| Topical term or geographic name as entry element |
Biology |
| General subdivision |
Data processing. |
|
|---|
| Topical term or geographic name as entry element |
Life Sciences. |
|
|---|
| Topical term or geographic name as entry element |
Systems Biology. |
|
|---|
| Topical term or geographic name as entry element |
Bioinformatics. |
|
|---|
| Topical term or geographic name as entry element |
Computer Appl. in Life Sciences. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Southgate, Jennifer. |
| Relator term |
editor. |
|
|---|
| Personal name |
Fuß, Hendrik. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Printed edition: |
| International Standard Book Number |
9781441979636 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-4419-7964-3 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Item type |
E-Book |
