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04584nam a22004095i 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
OSt |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20140310150234.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
fixed length control field |
cr nn 008mamaa |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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120615s2012 xxu| s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9781441996633 |
|
978-1-4419-9663-3 |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
RC321-580 |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
612.8 |
Edition number |
23 |
264 #1 - |
-- |
New York, NY : |
-- |
Springer New York : |
-- |
Imprint: Springer, |
-- |
2012. |
912 ## - |
-- |
ZDB-2-SBL |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Li, Yang V. |
Relator term |
editor. |
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
Title |
Metal Ion in Stroke |
Medium |
[electronic resource] / |
Statement of responsibility, etc |
edited by Yang V. Li, John H. Zhang. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
XVII, 820 p. 98 illus., 66 illus. in color. |
Other physical details |
online resource. |
440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE |
Title |
Springer Series in Translational Stroke Research |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
Preface -- Metal Ions In Stroke Pathophysiology -- Mechanisms Of Calcium Influx Following Stroke -- Mitochondrial Ca2+ Dysregulation During Stroke And Cell Death -- Calcium Channel Blockers And Stroke Prevention -- Calcium Dyshomeostasis In Astrocytes After Ischemia -- Calcium Signaling At The Blood-Brain Barrier In Stroke -- Zinc Overload In Stroke -- Intracellular Zinc Liberation: A Trigger For Oxidative Stress Induced Toxicity To Neurons And Neuroglia -- Zinc In Stroke: Time For A New Approach? -- Exploring The Zinc Metallome Of Cultured Cortical Neurons Using Synchroton Radiation X-Ray Fluorescence Microscopy -- Iron Neurotoxicity In Ischemic And Hemorrhagic Stroke -- Implication Of Oxidative Stress And “Labile Iron” In The Molecular Mechanisms Of Ischemic Stroke -- The Role Of Iron In Brain Following Subarachnoid Hemorrhage -- Iron Chelating Therapy In Stroke -- Iron Chelating Therapy In Stroke -- The Role Of Na+/Ca2+ Countertransport And Other Na+-Entry Routes In The Pathophysiology Of Stroke -- Sodium And Potassium MRI In Cerebral Ischemia -- The Impact Of Extracellular Potassium Accumulation In Stroke -- Potassium And Mitochondria -- Role Of A Changing Membrane Potential (Em) And Matching Blood Flow With Neuronal Activity -- The Role Of Potassium In Stroke, Cardiovascular Disease And Hypertension -- The Role Of Magnesium In The Pathophysiology And Treatment Of Stroke And Other Neurological Injuries -- The Role Of Magnesium In The Pathophysiology And Treatment Of Stroke And Other Neurological Injuries -- Magnesium And Neuroprotection In Stroke -- Magnesium In Ischemic Stroke And Subarachnoid Hemorrhage -- Selenium And Selenoproteins In Neuroprotection And Neuronal Cell Death -- Selenium As A Potential Treatment In Cardiac Arrest Induced Global Cerebral Ischemia -- The Neurochemical Alterations Associated With Manganese Toxicity -- Manganese Speciation Related To Neurotoxicity In Humans -- The Role Of Mitochondrial Oxidative Stress And ATP Depletion In The Pathology Of Manganese Toxicity -- Copper And Alzheimer Disease: The Good, The Bad And The Ugly -- Conjecturable Role Of Aluminum In Pathophysiology Of Stroke -- Chronic Arsenic Poisoning And Increased Risk Of Stroke -- Aspects Of Cadmium Neurotoxicity -- Cadmium Neurotoxicity And Its Role In Brain Disorders -- The Role Of Mercury And Cadmium In Cardiovascular Disease, Hypertension, And Stroke -- Nickel Modulation Of Voltage- And Ligand-Gated Ionic Channels In Neurons. |
520 ## - SUMMARY, ETC. |
Summary, etc |
This book illustrates remarkable roles of metal ions in the neuropathophysiology of stroke, which is a major cause of death and disability worldwide. Metal ions have unique chemical properties that allow them to play diverse roles in the brain. They regulate excitability and function as co-factors in cellular and genetic signaling pathways and therefore, have important roles ranging from essential to toxic. For the first time, the dyshomeostasis and pathophysiological actions of these metals in stroke are discussed systematically in thirty-six chapters in one volume. Highlighted metal ions include: Aluminum (Al) Arsenic (As) Cadmium (Cd) Calcium (Ca) Copper (Cu) Iron (Fe) Magnesium (Mg) Manganese (Mn) Mercury (Hg) Nickel (Ni) Potassium (K) Selenium (Se) Sodium (Na) Zinc (Zn) |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name as entry element |
Medicine. |
|
Topical term or geographic name as entry element |
Neurosciences. |
|
Topical term or geographic name as entry element |
Biomedicine. |
|
Topical term or geographic name as entry element |
Neurosciences. |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Zhang, John H. |
Relator term |
editor. |
710 2# - ADDED ENTRY--CORPORATE NAME |
Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
773 0# - HOST ITEM ENTRY |
Title |
Springer eBooks |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Display text |
Printed edition: |
International Standard Book Number |
9781441996626 |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-4419-9663-3 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
|
Item type |
E-Book |