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003 - CONTROL NUMBER IDENTIFIER |
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OSt |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20140310150236.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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120307s2012 xxu| s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9781461416807 |
|
978-1-4614-1680-7 |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
QR180-189.5 |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
616.079 |
Edition number |
23 |
264 #1 - |
-- |
New York, NY : |
-- |
Springer US, |
-- |
2012. |
912 ## - |
-- |
ZDB-2-SBL |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
López-Larrea, Carlos. |
Relator term |
editor. |
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
Title |
Self and Nonself |
Medium |
[electronic resource] / |
Statement of responsibility, etc |
edited by Carlos López-Larrea. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
XXII, 318p. 35 illus., 22 illus. in color. |
Other physical details |
online resource. |
440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE |
Title |
Advances in Experimental Medicine and Biology, |
International Standard Serial Number |
0065-2598 ; |
Volume number/sequential designation |
738 |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
The Origin of the Bacterial Immune Response -- The Evolution of Self During the Transition to Multicellularity -- Glyconectin Glycans as the Self-Assembling Nano-Molecular-Velcrosystem Mediating Self-Nonself Recognition and Adhesion Implicated in Evolution of Multicellularity -- Neglected Biological Features in Cnidarians Self-Nonself Recognition -- Intracellular Inflammatory Sensors For Foreign Invaders and Substances of Self-Origin -- Nonself Perception in Plant Innate Immunity -- How Did Flowering Plants Learn to Avoid Blind Date Mistakes? Self‑Incompatibility in Plants and Comparisons with Nonself Rejection in the Immune Response -- Signaling Pathways that Regulate Life and Cell Death: Evolution of Apoptosis in the Context of Self‑Defense -- Sensing Necrotic Cells -- Sensing Endoplasmic Reticulum Stress -- Autophagy and Self-Defense -- Viruses and Host Evolution: Virus‑Mediated Self Identity -- The Evolution of Adaptive Immunity -- Epigenetic Code and Self-Identity -- Viral Immunomodulatory Proteins: Usurping Host Genes as a Survival Strategy -- The Emergence of the Major Histocompatilibility Complex -- MHC Signaling During Social Communication. |
520 ## - SUMMARY, ETC. |
Summary, etc |
In 1960 Sir Frank Macfarlane Burnet received the Noble Prize in Physiology and Medicine. He titled his Nobel Lecture “Immunological Recognition of Self” emphasizing the central argument of immunological tolerance in “How does the vertebrate organism recognize self from nonself in this the immunological sense—and how did the capacity evolve.” The concept of self is linked to the concept of biological self identity. All organisms, from bacteria to higher animals, possess recognition systems to defend themselves from nonself. Even in the context of the limited number of metazoan phyla that have been studied in detail, we can now describe many of the alternative mechanism of immune recognition that have emerged at varying points in phylogeny. Two different arms—the innate and adaptive immune system—have emerged at different moments in evolution, and they are conceptually different. The ultimate goals of immune biology include reconstructing the molecular networks underlying immune processes. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name as entry element |
Medicine. |
|
Topical term or geographic name as entry element |
Immunology. |
|
Topical term or geographic name as entry element |
Biomedicine. |
|
Topical term or geographic name as entry element |
Immunology. |
|
Topical term or geographic name as entry element |
Biomedicine general. |
710 2# - ADDED ENTRY--CORPORATE NAME |
Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
773 0# - HOST ITEM ENTRY |
Title |
Springer eBooks |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Display text |
Printed edition: |
International Standard Book Number |
9781461416791 |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-4614-1680-7 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
|
Item type |
E-Book |