| 000 -LEADER |
|---|
| fixed length control field |
02787nam a22004455i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20140310150236.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
|---|
| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
120507s2012 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9781461434115 |
|
978-1-4614-3411-5 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
QH301-705 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
570 |
| Edition number |
23 |
| 264 #1 - |
|---|
| -- |
New York, NY : |
| -- |
Springer New York, |
| -- |
2012. |
| 912 ## - |
|---|
| -- |
ZDB-2-SBL |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Wellstead, Peter. |
| Relator term |
editor. |
| 245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Title |
Systems Biology of Parkinson's Disease |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc |
edited by Peter Wellstead, Mathieu Cloutier. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XVI, 176p. 42 illus., 21 illus. in color. |
| Other physical details |
online resource. |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Imaging of dopaminergic neurons and the implications for Parkinson’s disease -- Modelling and simulation of brain energy metabolism: energy and Parkinson's disease -- Systems Biology of Aging: Opportunities for Parkinson’s Disease -- Mitochondrion- and Endoplasmic Reticulum-Induced SK Channel Dysregulation as a Potential Origin of the Selective Neurodegeneration in Parkinson’s Disease -- Energetics of Ion Transport in Dopaminergic Substantia nigra Neurons: ion exchange dynamics at the pacemaking membrane -- Real-time In Vivo Sensing of Neurochemicals -- Modeling protein and oxidative metabolism in Parkinson's disease -- Mathematical Models of Dopamine Metabolism in Parkinson’s Disease -- Index. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
This text is the first to present a study of Parkinson’s disease from a Systems Biology perspective. By placing the condition at centre stage, the authors have been able to provide a wide ranging modelling and systems analysis that is focussed on a multi-facetted and highly complex condition. The book comprises a specially selected set of eight studies of important aspects of PD, covering all relevant scales of space and time. These are used to show how innovative sensing techniques, mathematical modelling, model analysis and computational simulation can throw new light on the dynamics of disease mechanisms that drive this important form of neurodegeneration. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Life sciences. |
|
|---|
| Topical term or geographic name as entry element |
Medicine. |
|
|---|
| Topical term or geographic name as entry element |
Neurosciences. |
|
|---|
| Topical term or geographic name as entry element |
Biological models. |
|
|---|
| Topical term or geographic name as entry element |
Life Sciences. |
|
|---|
| Topical term or geographic name as entry element |
Systems Biology. |
|
|---|
| Topical term or geographic name as entry element |
Neurosciences. |
|
|---|
| Topical term or geographic name as entry element |
Biomedicine general. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Cloutier, Mathieu. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Printed edition: |
| International Standard Book Number |
9781461434108 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-4614-3411-5 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Item type |
E-Book |
