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20140310150236.0 |
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120919s2013 xxu| s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9781461439912 |
|
978-1-4614-3991-2 |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
QP110.G45 |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
611.01816 |
Edition number |
23 |
264 #1 - |
-- |
New York, NY : |
-- |
Springer New York : |
-- |
Imprint: Springer, |
-- |
2013. |
912 ## - |
-- |
ZDB-2-SBL |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Dinman, Jonathan D. |
Relator term |
editor. |
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
Title |
Biophysical approaches to translational control of gene expression |
Medium |
[electronic resource] / |
Statement of responsibility, etc |
edited by Jonathan D. Dinman. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
XII, 317 p. 67 illus., 52 illus. in color. |
Other physical details |
online resource. |
440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE |
Title |
Biophysics for the Life Sciences ; |
Volume number/sequential designation |
1 |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
X-ray analysis of prokaryotic and eukaryotic ribosomes -- A passage through the ribosome by Cryo-EM -- Molecular dynamics simulations of the ribosome -- Structural analyses of the ribosome by chemical modification methods -- Methods for studying the interactions of translation factors with the ribosome -- Riboproteomic approaches to understanding IRES elements -- Rapid kinetic analysis of protein synthesis -- Investigating RNAs Involved in Translational Control by NMR and SAXS -- Analyses of RNA-ligand interactions by fluorescence anisotropy -- Approaches for the Identification and Characterization of RNA-Protein Interactions -- A multidisciplinary approach to RNA Localization -- Virtual Screening for RNA-interacting Small Molecules -- The ‘fifth’ RNA nucleotide: a role for ribosomal RNA pseudouridylation in control of gene expression at the translational level -- Translational Control of Synaptic Plasticity and Memory. |
520 ## - SUMMARY, ETC. |
Summary, etc |
When quantum mechanics was first proposed a century ago, nobody could have anticipated how deeply it would affect our lives. Today, we are connected and powered through devices whose existence is predicated on the basic principles of this strange physics. Not even the biological sciences have escaped its reach. As scientists query the deepest mysteries of the living world, the physical scales probed and the types of questions asked are increasingly blurring the lines between biology and physics. The hybrid field of biophysics represents the new frontier of the 21st century. The ribosome has been at the heart of three Nobel Prizes. Understanding its essential nature and how it interacts with other proteins and nucleic acids to control protein synthesis has been one of the central foundations in our understanding of the biology at the molecular level. With the advent of atomic scale structures, methods to visualize and separate individual molecules, and the computational power to model the complex interactions of over a million atoms at once, our understanding of how gene expression is controlled at the level of protein translation is now deeply ensconced in the biophysical realm. This book provides a premier resource to a wide audience, whether it be the general reader seeking a broad view of the field, a clinician interested in the role of protein translation in human disease, the bench researcher looking for state-of-the-art technologies, or computational scientists involved in cutting edge molecular modeling. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name as entry element |
Medicine. |
|
Topical term or geographic name as entry element |
Gene expression. |
|
Topical term or geographic name as entry element |
Biochemistry. |
|
Topical term or geographic name as entry element |
Nucleic acids. |
|
Topical term or geographic name as entry element |
Crystallography. |
|
Topical term or geographic name as entry element |
Biomedicine. |
|
Topical term or geographic name as entry element |
Gene Expression. |
|
Topical term or geographic name as entry element |
Biophysics and Biological Physics. |
|
Topical term or geographic name as entry element |
Biochemistry, general. |
|
Topical term or geographic name as entry element |
Single Molecule Studies, Molecular Motors. |
|
Topical term or geographic name as entry element |
Nucleic Acid Chemistry. |
|
Topical term or geographic name as entry element |
Crystallography. |
710 2# - ADDED ENTRY--CORPORATE NAME |
Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
773 0# - HOST ITEM ENTRY |
Title |
Springer eBooks |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Display text |
Printed edition: |
International Standard Book Number |
9781461439905 |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-4614-3991-2 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
|
Item type |
E-Book |