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Ten Years of Progress in GW/P Body Research (Record no. 17584)

000 -LEADER
fixed length control field 03220nam a22004815i 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140310150237.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 121207s2013 xxu| s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781461451075
978-1-4614-5107-5
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RB155-155.8
Classification number QH431
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 611.01816
Edition number 23
Classification number 599.935
Edition number 23
264 #1 -
-- New York, NY :
-- Springer New York :
-- Imprint: Springer,
-- 2013.
912 ## -
-- ZDB-2-SBL
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Chan, Edward K. L.
Relator term editor.
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE
Title Ten Years of Progress in GW/P Body Research
Medium [electronic resource] /
Statement of responsibility, etc edited by Edward K. L. Chan, Marvin J. Fritzler.
300 ## - PHYSICAL DESCRIPTION
Extent XI, 276 p. 47 illus., 25 illus. in color.
Other physical details online resource.
440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE
Title Advances in Experimental Medicine and Biology,
International Standard Serial Number 0065-2598 ;
Volume number/sequential designation 768
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Preface -- The GW body Story as an Example of Autoantibodies with Significant Impacts to Molecular Cell Biology -- The Discovery of GW Bodies -- The Discovery and Analysis of P Bodies -- Autoantibodies to Argonaute 2 (Su antigen) -- GW/P Bodies and Autoimmune Disease -- Function of GW182 and GW Bodies in siRNA and miRNA Pathways -- Post-Transcriptional Stimulation of Gene Expression by MicroRNAs -- Gawky (Gw) is the Drosophila Melanogaster GW182 Homologue -- The Role of GW182 Proteins in miRNA-mediated Gene Silencing -- Quantifying Argonaute Proteins in and out of GW/P-bodies: Implications in microRNA Activities -- Deadenylation and P-bodies -- Relationship of GW/P-bodies with Stress Granules -- Relationship of other Cytoplasmic Ribonucleoprotein (RNP) Bodies to GW/P Bodies -- A SNP in the Trinucleotide Repeat Region of the TNRC6A Gene Maps to a Major TNGW1 Autoepitope in Patients with Autoantibodies to GW182 -- Reflections on Ten Years of History of, and Future Prospects for, GW182 and GW/P Body Research -- Index.
520 ## - SUMMARY, ETC.
Summary, etc GW bodies are novel cytoplasmic foci that were discovered and named by Dr. Chan’s group in 2002. These bodies are now known to be active cytoplasmic foci involved with the new gene regulation process mediated by microRNA that leads to translational repression and mRNA degradation. The detailed biological functions of these cytoplasmic structures are still being uncovered and the idea for this book is to provide the history of the discovery and the major work from different laboratories that has led to the characterization and elucidation of the structure and function of these new multiple subcellular structures.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
Topical term or geographic name as entry element Human genetics.
Topical term or geographic name as entry element Biochemistry.
Topical term or geographic name as entry element Cytology.
Topical term or geographic name as entry element Biomedicine.
Topical term or geographic name as entry element Human Genetics.
Topical term or geographic name as entry element Cell Biology.
Topical term or geographic name as entry element Biochemistry, general.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Fritzler, Marvin J.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9781461451068
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-1-4614-5107-5
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Item type E-Book
Copies
Price effective from Permanent location Date last seen Not for loan Date acquired Source of classification or shelving scheme Koha item type Damaged status Lost status Withdrawn status Current location Full call number
2014-04-05AUM Main Library2014-04-05 2014-04-05 E-Book   AUM Main Library611.01816