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Prions and Diseases (Record no. 17589)

000 -LEADER
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003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140310150237.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
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020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781461453055
978-1-4614-5305-5
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RC321-580
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 612.8
Edition number 23
264 #1 -
-- New York, NY :
-- Springer New York :
-- Imprint: Springer,
-- 2013.
912 ## -
-- ZDB-2-SBL
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Zou, Wen-Quan.
Relator term editor.
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE
Title Prions and Diseases
Medium [electronic resource] :
Remainder of title Volume 1, Physiology and Pathophysiology /
Statement of responsibility, etc edited by Wen-Quan Zou, Pierluigi Gambetti.
300 ## - PHYSICAL DESCRIPTION
Extent IX, 241 p. 36 illus., 28 illus. in color.
Other physical details online resource.
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Transmissible Spongiform Encephalopathy: from the High Middle Ages to Daniel Carlton Gajdusek -- The Rich Chemistry of the Copper and Zinc Sites in Cellular Prion Protein -- Role of Cellular Prion Protein in the Amyloid-ß Oligomer Pathophysiology of Alzheimer’s Disease -- Cellular Prion Protein and Cancers -- Insoluble Cellular Prion Protein -- Protein Misfolding Cyclic Amplification -- Cofactor Involvement in Prion Propagation -- Prion Protein Conversion and Lipids -- New Perspectives on Prion Conversion: Introducing a Mechanism of Deformed Templating -- Infectious and Pathogenic Forms of Prion Protein -- Cellular Mechanisms of Propagation and Clearance -- Molecular Mechanisms Encoding Quantitative and Qualitative Traits of Prion Strains -- Modeling the Cell Biology of Prions -- Prion Strain Interference -- Introduction to Yeast and Fungal Prions -- Yeast Prions are Pathogenic, in-register Parallel Amyloids.
520 ## - SUMMARY, ETC.
Summary, etc Transmissible spongiform encephalopathies (TSE), now broadly known as prion diseases, have been recognized for nearly 300 years in animals and almost 100 years in humans. However, the nature of the transmissible agent had largely remained a mystery until Stanley Prusiner discovered the infectious isoform of the prion protein (PrP), named prion or scrapie PrP (PrPSc), in 1982. The subsequent modern studies with protein chemistry and molecular biology in cell culture, transgenic animals, and cell-free systems, including the revolutionary protein-misfolding cyclic amplification (PMCA), have greatly advanced our understanding of the pathogenesis of prion diseases and facilitated the identification of new prion diseases in animals and humans. In Prions and Prion Diseases, more than 60 leading researchers and clinicians worldwide provide an up-to-date development in many aspects of these unique infectious pathogens and their associated diseases. Volume I highlights the association of the cellular prion protein (PrPC) with copper and zinc, the potential roles of PrPC in Alzheimer’s disease and cancers, insoluble PrPC, PMCA, molecular and cellular mechanisms of PrPSc formation and clearance, possible co-factors involved in the conversion of PrPC into PrPSc, infectious and pathogenic forms of PrP, cell biology of prions, prion strains and their interference, as well as yeast prions and their inheritable and structural traits. This unique volume covers history from the high Middle Ages to the TSE era of Daniel Carleton Gajdusek, followed by the prion era of Stanley Prusiner whose extraordinary discovery opened a new chapter in prion research. Volume I will take you through the fascinating chronicle of prions in mammals, yeast, and fungi.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
Topical term or geographic name as entry element Human physiology.
Topical term or geographic name as entry element Neurosciences.
Topical term or geographic name as entry element Neurology.
Topical term or geographic name as entry element Biochemistry.
Topical term or geographic name as entry element Animal Physiology.
Topical term or geographic name as entry element Biomedicine.
Topical term or geographic name as entry element Neurosciences.
Topical term or geographic name as entry element Human Physiology.
Topical term or geographic name as entry element Neurology.
Topical term or geographic name as entry element Protein Science.
Topical term or geographic name as entry element Animal Physiology.
Topical term or geographic name as entry element Biochemistry, general.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Gambetti, Pierluigi.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9781461453048
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-1-4614-5305-5
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Item type E-Book
Copies
Price effective from Permanent location Date last seen Not for loan Date acquired Source of classification or shelving scheme Koha item type Damaged status Lost status Withdrawn status Current location Full call number
2014-04-05AUM Main Library2014-04-05 2014-04-05 E-Book   AUM Main Library612.8