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OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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20140310150238.0 |
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130706s2013 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9781461477594 |
|
978-1-4614-7759-4 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
RC321-580 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
612.8 |
| Edition number |
23 |
| 264 #1 - |
|---|
| -- |
New York, NY : |
| -- |
Springer New York : |
| -- |
Imprint: Springer, |
| -- |
2013. |
| 912 ## - |
|---|
| -- |
ZDB-2-SBL |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Borisova, Tatiana. |
| Relator term |
author. |
| 245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Title |
Cholesterol and Presynaptic Glutamate Transport in the Brain |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc |
by Tatiana Borisova. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XVI, 75 p. 32 illus., 11 illus. in color. |
| Other physical details |
online resource. |
| 440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE |
|---|
| Title |
SpringerBriefs in Neuroscience, |
| International Standard Serial Number |
2191-558X ; |
| Volume number/sequential designation |
12 |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Presynaptic glutamate transport in the brain -- Cholesterol and its role in synaptic transmission -- Effects of cholesterol-depleting agent methyl-b-cyclodextrin (MbCD) on the functional state of brain nerve terminals -- The extracellular level and uptake of glutamate in cholesterol-deficient nerve terminals -- Unstimulated and exocytotic glutamate release from cholesterol-deficient nerve terminals -- Neuroprotection by lowering cholesterol. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
Glutamate is the primary excitatory neurotransmitter in the CNS and disturbances in glutamate transport contribute to a number of neurological and neurodegenerative disorders. Appropriate levels of cholesterol are very important for the proper functioning of glutamate transport while unbalanced levels of cholesterol have been implicated in the pathogenesis of disorders such as stroke, ischemia, traumatic brain injury, and neurotoxicity. In the proposed book, the author presents data from the literature and from her own lab to address the extent to and way in which membrane cholesterol modulates presynaptic glutamate transport and whether lowering the level of cholesterol available can offer some neuroprotective benefits. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Medicine. |
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| Topical term or geographic name as entry element |
Neurosciences. |
|
|---|
| Topical term or geographic name as entry element |
Neurochemistry. |
|
|---|
| Topical term or geographic name as entry element |
Biomedicine. |
|
|---|
| Topical term or geographic name as entry element |
Neurosciences. |
|
|---|
| Topical term or geographic name as entry element |
Neurochemistry. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Printed edition: |
| International Standard Book Number |
9781461477587 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-4614-7759-4 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Item type |
E-Book |
