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20140310150238.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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130814s2013 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9781461480082 |
|
978-1-4614-8008-2 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
QH301-705 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
570 |
| Edition number |
23 |
| 264 #1 - |
|---|
| -- |
New York, NY : |
| -- |
Springer New York : |
| -- |
Imprint: Springer, |
| -- |
2013. |
| 912 ## - |
|---|
| -- |
ZDB-2-SBL |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Vodovotz, Yoram. |
| Relator term |
editor. |
| 245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Title |
Complex Systems and Computational Biology Approaches to Acute Inflammation |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc |
edited by Yoram Vodovotz, Gary An. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XI, 291 p. 54 illus., 29 illus. in color. |
| Other physical details |
online resource. |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
An overview of the Translational Dilemma and the need for Translational Systems Biology of inflammation -- Part I: Complex Systems Methods and Applications -- Translational Equation-based Modeling -- Agent-based Modeling in Translational Systems Biology -- Analysis of Heart Rate Variability -- Analysis of Ventilatory Pattern Variability -- Part II: Translational Modeling of Sepsis and Trauma -- Disorder of Systemic Inflammation in Sepsis and Trauma: A Systems Perspective -- Multi-scale equation-based models: Insights for Inflammation and Physiological Variability -- Integrating Data Driven and Mechanistic Models of the Inflammatory Response in Sepsis and Trauma -- In silico Trials and Personalized Therapy for Sepsis and Trauma -- Part III: Translational Modeling of Wound Healing -- Disorder of Localized Inflammation in Wound Healing: A Systems Perspective -- Equation-based Models of Wound Healing and Collective Cell Migration -- Agent-based Models of Wound Healing -- Part IV: Translational Modeling of Host-pathogen Interactions -- Modeling Host-Pathogen Interactions in Necrotizing Enterocolitis -- Modeling Host-Vector-Pathogen Immuno-inflammatory Interactions in Malaria -- Part V: Future Perspectives -- Translation to Implementation -- The Rationale and Implementation of Translational Systems Biology as a new Paradigm for the Study of Inflammation -- Index. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
The Translational Dilemma, the difficulty in achieving effective translation of basic mechanistic biomedical knowledge into effective therapeutics, is the greatest challenge in biomedical research. Nowhere is this more apparent than in understanding and manipulating the acute inflammatory response in the settings of sepsis, trauma/hemorrhage, wound healing, and related processes. The burgeoning fields of complex systems analysis and computational biology offer researchers a pathway towards addressing the Translational Dilemma. Complex Systems and Computational Biology Approaches to Acute Inflammation presents the current state of the art of multi-disciplinary and systems-oriented research approaches to complex diseases arising from and driven by the acute inflammatory response. The chapters in this volume provide an introduction to different types of computational modeling, and how these methods can be applied to specific inflammatory diseases, with a focus on providing readers with a roadmap for integrating advanced mathematical and computational techniques with traditional experimental methods. By presenting the role of computational modeling as an integrated component of the research process, Complex Systems and Computational Biology Approaches to Acute Inflammation offers a window into the future of biomedical research. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Life sciences. |
|
|---|
| Topical term or geographic name as entry element |
Medicine. |
|
|---|
| Topical term or geographic name as entry element |
Immunology. |
|
|---|
| Topical term or geographic name as entry element |
Biological models. |
|
|---|
| Topical term or geographic name as entry element |
Life Sciences. |
|
|---|
| Topical term or geographic name as entry element |
Systems Biology. |
|
|---|
| Topical term or geographic name as entry element |
Immunology. |
|
|---|
| Topical term or geographic name as entry element |
Biomedicine general. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
An, Gary. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Printed edition: |
| International Standard Book Number |
9781461480075 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-4614-8008-2 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Item type |
E-Book |
