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New Strategies in Stroke Intervention (Record no. 17745)

000 -LEADER
fixed length control field 04440nam a22005055i 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140310150239.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 100301s2010 xxu| s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781607612803
978-1-60761-280-3
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RC321-580
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 612.8
Edition number 23
264 #1 -
-- Totowa, NJ :
-- Humana Press,
-- 2010.
912 ## -
-- ZDB-2-SBL
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Annunziato, Lucio.
Relator term editor.
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE
Title New Strategies in Stroke Intervention
Medium [electronic resource] :
Remainder of title Ionic Transporters, Pumps, and New Channels /
Statement of responsibility, etc edited by Lucio Annunziato.
300 ## - PHYSICAL DESCRIPTION
Extent XV, 254p. 12 illus., 6 illus. in color.
Other physical details online resource.
440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE
Title Contemporary Neuroscience
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Basis of Ionic Dysregulation in Cerebral Ischemia -- Why have Ionotropic and Metabotropic Glutamate Antagonists Failed in Stroke Therapy? -- Mitochondrial Channels as Potential Targets for Pharmacological Strategies in Brain Ischemia -- Endoplasmic Reticulum Calcium Homeostasis and Neuronal Pathophysiology of Stroke -- The Na + /Ca 2+ Exchanger: A Target for Therapeutic Intervention in Cerebral Ischemia -- The “Loop” Diuretic Drug Bumetanide-Sensitive Na + -K + -Cl - Cotransporter in Cerebral Ischemia -- The Na + /H + Exchanger: A Target for Therapeutic Intervention in Cerebral Ischemia -- The Na + /K + -ATPase as a Drug Target for Ischemic Stroke -- Acid-Sensing Ion Channels (ASICs): New Targets in Stroke Treatment -- Role of TRPM7 in Ischemic CNS Injury -- Subtypes of Voltage-Gated Ca 2+ Channels and Ischemic Brain Injury -- The Diverse Roles of K + Channels in Brain Ischemia -- Clinical Trials with Drugs Targeting Ionic Channels, Antiporters, and Pumps in Ischemic Stroke.
520 ## - SUMMARY, ETC.
Summary, etc Ischemic brain damage represents a major source of morbidity and mortality in westernized society and poses a significant financial burden on the health care system. To date, few effective therapies have been realized to treat stroke and promising avenues have not proven clinically useful. Recent evidence, however, suggests that channels, pumps, and ionic exchangers are involved in CNS ischemia and ischemic stroke, but the potential contribution of these channels for curing stroke is far less understood than for many other normal and pathological conditions. New Strategies in Stroke Intervention: Ionic Channels, Pumps, and Transporters analyzes the roles played by targets in stroke development and the potential action of drugs modulating these proteins. This book provides a groundbreaking review of these ionic channels, pumps, and transporters as regulators of neuronal ionic homeostasis, providing a better understanding of ischemic brain disorders and the new pharmacological avenues for a cure. It will be a useful tool for researchers working in this field, and any student interested in the physiological, pathophysiological, and pharmacological features of stroke damage. About the Editor: Lucio Annunziato is a professor of pharmacology in the School of Medicine at the University of Naples ‘‘Federico II’’, Italy. He is coordinator of the University's neuroscience Ph.D. program and director of the Department of Neuroscience. He is also the president elect of the Italian Society of Neuroscience. Dr. Annunziato has authored more than 150 full papers and his scientific interest is mainly devoted to the molecular pharmacology of plasma membrane transporters and ionic channels involved in the pathophysiology of stroke. Most of his recent papers have appeared in the most qualified international journals in the field of ischemic neurodegeneration.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
Topical term or geographic name as entry element Neurosciences.
Topical term or geographic name as entry element Toxicology.
Topical term or geographic name as entry element Anesthesiology.
Topical term or geographic name as entry element Cardiology.
Topical term or geographic name as entry element Neurology.
Topical term or geographic name as entry element Biomedicine.
Topical term or geographic name as entry element Neurosciences.
Topical term or geographic name as entry element Neurology.
Topical term or geographic name as entry element Cardiology.
Topical term or geographic name as entry element Molecular Medicine.
Topical term or geographic name as entry element Pharmacology/Toxicology.
Topical term or geographic name as entry element Anesthesiology.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9781607612797
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-1-60761-280-3
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Item type E-Book
Copies
Price effective from Permanent location Date last seen Not for loan Date acquired Source of classification or shelving scheme Koha item type Damaged status Lost status Withdrawn status Current location Full call number
2014-04-05AUM Main Library2014-04-05 2014-04-05 E-Book   AUM Main Library612.8
Languages: 
English |
العربية