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5-HT2C Receptors in the Pathophysiology of CNS Disease (Record no. 17762)

000 -LEADER
fixed length control field 05121nam a22005175i 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140310150239.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 101130s2011 xxu| s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781607619413
978-1-60761-941-3
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RC321-580
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 612.8
Edition number 23
264 #1 -
-- Totowa, NJ :
-- Humana Press :
-- Imprint: Humana Press,
-- 2011.
912 ## -
-- ZDB-2-SBL
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Di Giovanni, Giuseppe.
Relator term editor.
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE
Title 5-HT2C Receptors in the Pathophysiology of CNS Disease
Medium [electronic resource] /
Statement of responsibility, etc edited by Giuseppe Di Giovanni, Ennio Esposito, Vincenzo Di Matteo.
300 ## - PHYSICAL DESCRIPTION
Extent XII, 560 p.
Other physical details online resource.
440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE
Title The Receptors ;
Volume number/sequential designation 22
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note The making of the 5-HT2C receptor -- Serotonin 5-HT2C receptors: chemical neuronatomy in the mammalian brain -- The medicinal chemistry of 5-HT2C receptor ligands -- Insights into 5-HT2C receptor function gained from transgenic mouse models -- Serotonin 5-HT2C receptor signal transduction -- Homology modeling of 5-HT2C receptors -- 5-HT2C receptor dimerization -- RNA editing of 5-HT2C receptor and neuropsychiatric diseases -- Serotonergic control of adult neurogenesis: focus on 5-HT2C receptors -- The constitutive activity of 5-HT2C receptors as an additional modality of interaction of the serotonergic system -- The 5-HT2C receptor subtype controls central dopaminergic systems: evidence from electrophysiological and neurochemical studies -- The role of serotonin-2C receptors in the pathophysiology of depression -- 5-HT2C receptors and suicidal behaviour -- The 5-HT2C receptor as a target for schizophrenia -- Serotonin and reward-related behaviour: focus on 5-HT2C receptors -- Tat-3L4F: a novel peptide for treating drug addiction by disrupting interaction between PTEN and 5-HT2C receptor -- The role of serotonin in eating behaviour: focus on 5-HT2C receptors -- Physiological and pathophysiological aspects of 5-HT2C receptors in basal ganglia -- Modeling tardive dyskinesia: predictive 5-HT2C receptor antagonist treatment -- The role of 5-HT2A/2C receptors in sleep and waking -- Role of alternative splicing of the 5-HT2C in the Prader-Willi syndrome -- The role of 5-HT2C receptor in epilepsy -- The role of serotonin on attentional processes and executive functioning: focus on 5-HT2C receptors -- 5-HT2C receptors in learning -- The role of 5-HT2C polymorphisms in behavioural and psychological symptoms of alzheimer's disease -- Ocular hypotension: involvement of serotonergic 5-HT2C receptors.
520 ## - SUMMARY, ETC.
Summary, etc Research of 5-HT2c receptors stretches back twenty-five years, and while much of it has been productive, the past decade of research has been extraordinary in terms of both amount produced and insights gained. It is hardly surprising that 5-HT2c receptor research has grown so fruitful, given that it is a prominent central serotonin receptor subtype widely expressed within the central and the peripheral nervous system and is thought to play a major role in the regulation of numerous behaviors. It has further been shown by experimental and clinical observation that it may represent a possible therapeutic target for the development of drugs for a range of central nervous system disorders. The time, therefore, is more than appropriate to offer the first ever overview of the research of 5-HT2c receptors. Part of the popular and important series, “The Receptors,” The 5-HT2c Receptor provides a thorough update of the functional status of the 5-HT2c receptor. It covers the molecular, cellular, anatomical, biochemical and behavioral aspects of this receptor so as to highlight its distinctive regulatory properties and the emerging functional significance of constitutive activity and RNA-editing in vivo. In addition, the book investigates the receptors’ therapeutic potential in a range of different diseases, treated individually in separate chapters, including depression, drug abuse, schizophrenia, eating disorders, Parkinson’s disease, Prader-Willi Syndrome, Alzheimer’s disease and epilepsy. While not exhaustive, this text is a vital tool in understanding the past and inspiring the future of interdisciplinary research on the 5-HT2c receptor.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
Topical term or geographic name as entry element Human physiology.
Topical term or geographic name as entry element Neurosciences.
Topical term or geographic name as entry element Toxicology.
Topical term or geographic name as entry element Neurology.
Topical term or geographic name as entry element Neurobiology.
Topical term or geographic name as entry element Biomedicine.
Topical term or geographic name as entry element Neurosciences.
Topical term or geographic name as entry element Pharmacology/Toxicology.
Topical term or geographic name as entry element Human Physiology.
Topical term or geographic name as entry element Neurobiology.
Topical term or geographic name as entry element Neurology.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Esposito, Ennio.
Relator term editor.
Personal name Di Matteo, Vincenzo.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9781607619406
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-1-60761-941-3
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Item type E-Book
Copies
Price effective from Permanent location Date last seen Not for loan Date acquired Source of classification or shelving scheme Koha item type Damaged status Lost status Withdrawn status Current location Full call number
2014-04-05AUM Main Library2014-04-05 2014-04-05 E-Book   AUM Main Library612.8

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