| 000 -LEADER |
|---|
| fixed length control field |
03339nam a22004695i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20140310150239.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
|---|
| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
120420s2012 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9781617797880 |
|
978-1-61779-788-0 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
QH573-671 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
571.6 |
| Edition number |
23 |
| 264 #1 - |
|---|
| -- |
Totowa, NJ : |
| -- |
Humana Press : |
| -- |
Imprint: Humana Press, |
| -- |
2012. |
| 912 ## - |
|---|
| -- |
ZDB-2-SBL |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Kavallaris, Maria. |
| Relator term |
editor. |
| 245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Title |
Cytoskeleton and Human Disease |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc |
edited by Maria Kavallaris. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XXIV, 453p. 63 illus., 42 illus. in color. |
| Other physical details |
online resource. |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Actin -- Microtubules -- The Kinesin Superfamily -- Myosins -- The Actin Cytoskeleton and Membrane Organisation in T Lymphocytes -- Thin Filament Disease of Stricted Muscle -- Filamin and disease -- LIMK and Cancer Metastasis -- Actin Mutations and Deafness -- Therapeutic Targeting of the Actin Cytoskeleton -- Microtubules as a Target in Cancer Therapy -- Microtubules and drug resistance -- Posttranslational Modifications of Tubulin -- Stathmin and Cancer -- The Biology and Pathobiology of Tau Protein -- Tubulin-Related Malformations of Cortical Development -- Spectrins in Human Diseases -- Laminopathies -- Desmin and Heart Disease -- Neurodegenerative Diseases and Intermediate Filaments. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
The cytoskeleton is made up of a large variety of specialized proteins and is a highly dynamic system that is involved in the majority of key cellular events. It is now clear that the cytoskeleton is often associated, and has diverse roles in human disease. Emerging understanding of the molecular and cellular events that drive cytoskeletal mediated disease including cancer, heart disease, myopathies, neurodegenerative diseases and skin disorders, are also helping shape targeted therapeutic approaches to treat these diseases. Cytoskeleton and Human Disease Book Summary reviews the key components, mechanisms and clinical implications of cytoskeletal defects in disease. Contributed by leading investigators in their respective fields, the chapters include topics associated with the basics of the cytoskeleton, actin-associated disease states, microtubule-associated disease states and intermediate filament-associated disease states. This authoritative volume is intended for a wide audience of clinicians, researchers and students with an interest in the application of biomedical research to the understanding and management of disease states associated with the cytoskeleton. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Life sciences. |
|
|---|
| Topical term or geographic name as entry element |
Oncology. |
|
|---|
| Topical term or geographic name as entry element |
Biochemistry. |
|
|---|
| Topical term or geographic name as entry element |
Cytology. |
|
|---|
| Topical term or geographic name as entry element |
Cell cycle. |
|
|---|
| Topical term or geographic name as entry element |
Life Sciences. |
|
|---|
| Topical term or geographic name as entry element |
Cell Biology. |
|
|---|
| Topical term or geographic name as entry element |
Cell Cycle Analysis. |
|
|---|
| Topical term or geographic name as entry element |
Cell Physiology. |
|
|---|
| Topical term or geographic name as entry element |
Biochemistry, general. |
|
|---|
| Topical term or geographic name as entry element |
Cancer Research. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Printed edition: |
| International Standard Book Number |
9781617797873 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-61779-788-0 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Item type |
E-Book |
