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03218nam a22004815i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20140310150239.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
110331s2011 xxk| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9781848826441 |
|
978-1-84882-644-1 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
RB155-155.8 |
|
|---|
| Classification number |
QH431 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
611.01816 |
| Edition number |
23 |
|
|---|
| Classification number |
599.935 |
| Edition number |
23 |
| 264 #1 - |
|---|
| -- |
London : |
| -- |
Springer London : |
| -- |
Imprint: Springer, |
| -- |
2011. |
| 912 ## - |
|---|
| -- |
ZDB-2-SBL |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Roach, Helmtrud I. |
| Relator term |
editor. |
| 245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Title |
Epigenetic Aspects of Chronic Diseases |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc |
edited by Helmtrud I. Roach, Felix Bronner, Richard O.C. Oreffo. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XVIII, 238p. 48 illus., 42 illus. in color. |
| Other physical details |
online resource. |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Epigenetics and Chronic Diseases: An Overview -- Techniques to Study DNA Methylation and Histone Modification -- Mechanisms of Epigenetic Gene Silencing -- Mechanisms of Epigenetic Gene Activation in Disease: Dynamics of DNA Methylation and Demethylation -- The Role of Histone Demethylases in Disease -- Autoimmune Diseases -- Epigenetics of Rheumatoid Arthritis -- DNA Methylation Changes in Osteoarthritis -- Epigenetics and Type 2 Diabetes -- Epigenetic Regulation of Asthma and Allergic Diseases -- Epigenetics in Psychiatry -- Epigenetics and Late-Onset Alzheimer’s Disease -- Epigenetic Mechanisms in the Developmental Origins of Adult Disease -- Targeting Histone Deacetylases in Chronic Obstructive Pulmonary Disease -- Clinical Trials of Epigenetic Modifiers in the Treatment of Myelodysplastic Syndrome. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
Epigenetic Aspects of Chronic Diseases assembles in comprehensive form what is known about the role of epigenetics in chronic disease development. This book provides new insights into treatment, including modulation of epigenetic regulation. Each chapter gives an outline of a respective disease, explains why epigenetics may be involved in the disease process and then presents the evidence of how changes in epigenetic status contribute to initiation and progress of the disease. The final chapters look towards future therapeutic treatment, based on manipulation of epigenetic aspects. Written by widely published experts, Epigenetic Aspects of Chronic Diseases is a valuable reference tool for clinicians and researchers who investigate and treat chronic diseases, as well as health care personnel, post-doctoral fellows and medical or dental students. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Medicine. |
|
|---|
| Topical term or geographic name as entry element |
Human genetics. |
|
|---|
| Topical term or geographic name as entry element |
Internal medicine. |
|
|---|
| Topical term or geographic name as entry element |
Biochemistry. |
|
|---|
| Topical term or geographic name as entry element |
Biomedicine. |
|
|---|
| Topical term or geographic name as entry element |
Human Genetics. |
|
|---|
| Topical term or geographic name as entry element |
Medical Biochemistry. |
|
|---|
| Topical term or geographic name as entry element |
Internal Medicine. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Bronner, Felix. |
| Relator term |
editor. |
|
|---|
| Personal name |
Oreffo, Richard O.C. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Printed edition: |
| International Standard Book Number |
9781848826434 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-84882-644-1 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Item type |
E-Book |
