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Matrix Metalloproteinase Inhibitors (Record no. 17823)

000 -LEADER
fixed length control field 02861nam a22003975i 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140310150240.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 120404s2012 sz | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783034803649
978-3-0348-0364-9
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RC321-580
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 612.8
Edition number 23
264 #1 -
-- Basel :
-- Springer Basel,
-- 2012.
912 ## -
-- ZDB-2-SBL
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Gupta, Satya Prakash.
Relator term editor.
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE
Title Matrix Metalloproteinase Inhibitors
Medium [electronic resource] :
Remainder of title Specificity of Binding and Structure-Activity Relationships /
Statement of responsibility, etc edited by Satya Prakash Gupta.
300 ## - PHYSICAL DESCRIPTION
Extent X, 285p. 184 illus., 11 illus. in color.
Other physical details online resource.
440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE
Title Experientia Supplementum,
International Standard Serial Number 1023-294X ;
Volume number/sequential designation 103
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Matrix Metalloproteinases -- Specificity of Binding with Matrix Metalloproteinases -- The Gelatinases and Their Inhibitors: The Structure–Activity Relationships -- Advances in Studies on Collagenase Inhibitors -- Hydroxamic Acids as Matrix Metalloproteinase Inhibitors -- Quantitative Structure–Activity Relationship Studies on Sulfonamide-Based MMP Inhibitors -- Matrix Metalloproteinase Inhibitors as Investigative Tools in the Pathogenesis and Management of Vascular Disease.
520 ## - SUMMARY, ETC.
Summary, etc Matrix metalloproteinases (MMPs) are proteolytic enzymes that are involved in many physiological and pathological processes. The field of MMP research is very important due to the implications of the distinct paralogs in both human physiology and pathology. Over-activation of these enzymes results in tissue degradation, producing a wide array of disease processes such as rheumatoid arthritis, osteoarthritis, tumor growth and metastasis, multiple sclerosis, congestive heart failure, and others. Thus MMP inhibitors are candidates for therapeutic agents to combat a number of diseases.   The present book discusses the design and development of different classes of inhibitors of important classes of MMPs, such as gelatinases and collagenases. The articles focus specifically on structure-activity relationships of all classes of compounds and on their modes of action and specificity of binding with the receptors based on experimental and theoretical studies. These studies constitute a valuable asset for all those involved in drug development.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
Topical term or geographic name as entry element Neurosciences.
Topical term or geographic name as entry element Biomedicine.
Topical term or geographic name as entry element Neurosciences.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9783034803632
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-3-0348-0364-9
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Item type E-Book
Copies
Price effective from Permanent location Date last seen Not for loan Date acquired Source of classification or shelving scheme Koha item type Damaged status Lost status Withdrawn status Current location Full call number
2014-04-05AUM Main Library2014-04-05 2014-04-05 E-Book   AUM Main Library612.8