000 -LEADER |
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03727nam a22004455i 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
OSt |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20140310150240.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
fixed length control field |
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008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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140131s2013 gw | s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9783319042411 |
|
978-3-319-04241-1 |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
QR1-502 |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
579 |
Edition number |
23 |
264 #1 - |
-- |
Cham : |
-- |
Springer International Publishing : |
-- |
Imprint: Springer, |
-- |
2013. |
912 ## - |
-- |
ZDB-2-SBL |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Rosenberg, Eugene. |
Relator term |
author. |
245 14 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
Title |
The Hologenome Concept: Human, Animal and Plant Microbiota |
Medium |
[electronic resource] / |
Statement of responsibility, etc |
by Eugene Rosenberg, Ilana Zilber-Rosenberg. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
XIII, 178 p. |
Other physical details |
online resource. |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
Introduction: Symbioses and the Hologenome Concept -- Origin of Prokaryotes and Eukaryotes -- Abundance and Diversity of Microbiota -- Microbiotas are Transmitted between Holobiont Generations -- Microbiotas are Part of Holobiont Fitness -- Variation in Holobionts -- Viruses are part of the Holobiont`s Fitness and Evolution -- Evolution of Holobionts -- Pathogens as Symbionts -- Prebiotics, Probiotics, Synbiotics and Phage Therapy -- Epilogue. |
520 ## - SUMMARY, ETC. |
Summary, etc |
Groundbreaking research over the last 10 years has given rise to the hologenome concept of evolution. This concept posits that the holobiont (host plus all of its associated microorganisms) and its hologenome (sum of the genetic information of the host and its symbiotic microorganisms), acting in concert, function as a unique biological entity and therefore as a level of selection in evolution. All animals and plants harbor abundant and diverse microbiota, including viruses. Often the amount of symbiotic microorganisms and their combined genetic information far exceed that of their host. The microbiota with its microbiome, together with the host genome, can be transmitted from one generation to the next and thus propagate the unique properties of the holobiont. The microbial symbionts and the host interact in a cooperative way that affects the health of the holobiont within its environment. Beneficial microbiota protects against pathogens, provides essential nutrients, catabolizes complex polysaccharides, renders harmful chemicals inert, and contributes to the performance of the immune system. In humans and animals, the microbiota also plays a role in behavior. The sum of these cooperative interactions characterizes the holobiont as a unique biological entity. Genetic variation in the hologenome can be brought about by changes in either the host genome or the microbial population genomes (microbiome). Evolution by cooperation can occur by amplifying existing microbes, gaining novel microbiota and by acquiring microbial and viral genes. Under environmental stress, the microbiome can change more rapidly and in response to more processes than the host organism alone and thus influences the evolution of the holobiont. Prebiotics, probiotics, synbiotics and phage therapy are discussed as applied aspects of the hologenome concept. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name as entry element |
Life sciences. |
|
Topical term or geographic name as entry element |
Evolution (Biology). |
|
Topical term or geographic name as entry element |
Microbiology. |
|
Topical term or geographic name as entry element |
Zoology. |
|
Topical term or geographic name as entry element |
Life Sciences. |
|
Topical term or geographic name as entry element |
Microbiology. |
|
Topical term or geographic name as entry element |
Evolutionary Biology. |
|
Topical term or geographic name as entry element |
Zoology. |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Zilber-Rosenberg, Ilana. |
Relator term |
author. |
710 2# - ADDED ENTRY--CORPORATE NAME |
Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
773 0# - HOST ITEM ENTRY |
Title |
Springer eBooks |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Display text |
Printed edition: |
International Standard Book Number |
9783319042404 |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-3-319-04241-1 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
|
Item type |
E-Book |