| 000 -LEADER |
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| fixed length control field |
03251nam a22004455i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20140310150241.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
100327s2010 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9783642114168 |
|
978-3-642-11416-8 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
RB155-155.8 |
|
|---|
| Classification number |
QH431 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
611.01816 |
| Edition number |
23 |
|
|---|
| Classification number |
599.935 |
| Edition number |
23 |
| 264 #1 - |
|---|
| -- |
Berlin, Heidelberg : |
| -- |
Springer Berlin Heidelberg, |
| -- |
2010. |
| 912 ## - |
|---|
| -- |
ZDB-2-SBL |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Dakubo, Gabriel D. |
| Relator term |
author. |
| 245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Title |
Mitochondrial Genetics and Cancer |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc |
by Gabriel D. Dakubo. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
X, 368p. 62 illus., 31 illus. in color. |
| Other physical details |
online resource. |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
General Overview of Mitochondrial Genetics and Functions -- Basic Mitochondrial Genetics, Bioenergetics, and Biogenesis -- The Warburg Phenomenon and Other Metabolic Alterations of Cancer Cells -- Mitochondrial Control of Apoptosis and Cancer -- Mitochondrial-to-Nuclear Communications in Cancer -- Mitochondrial Genetic Alterations in Cancer -- Types of Mitochondrial Genetic Alterations in Cancer -- Mitochondrial Genetic Alterations in Cancer I -- Mitochondrial Genetic Alterations in Cancer II -- Mitochondrial Genome Rearrangements and Copy Number Changes in Cancer -- Functional Importance of Mitochondrial Genetic Alterations in Cancer -- The Role of Mitochondrial Reactive Oxygen Species in Cancer -- Clinical Applications of Mitochondrial Genome Changes in Cancer -- Mitochondrial DNA Measurement in Exfoliated Cells for Cancer Detection and Monitoring: The Copy Number Advantage -- Early Cancer Detection and Monitoring Using Changes in the Mitochondrial Genome as Biosensors -- Analysis of Mitochondrial Genome Alterations in Cancer -- “Mitocans”: Agents Targeting Mitochondria to Kill Cancer Cells. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
The pivotal role of mitochondrial functions in carcinogenesis is quite well established. However, the critical role of mitochondrial genome alterations to cancer development is muted in traditional textbooks. Recent scientific efforts have provided unequivocal evidence for mitochondrial genome mutations and content changes in cancer development, progression, and therapy. This pioneering book is a unique compilation of mitochondrial genome alterations in cancer. While primarily focused on the emerging role of mitochondrial genome changes, bioenergetics and signaling pathways, attention is also given to the metabolic transformations of the cancer cell, as well as the established altered cell death processes that underlie cancer evolution and treatment resistance. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Medicine. |
|
|---|
| Topical term or geographic name as entry element |
Oncology. |
|
|---|
| Topical term or geographic name as entry element |
Human genetics. |
|
|---|
| Topical term or geographic name as entry element |
Biomedicine. |
|
|---|
| Topical term or geographic name as entry element |
Human Genetics. |
|
|---|
| Topical term or geographic name as entry element |
Molecular Medicine. |
|
|---|
| Topical term or geographic name as entry element |
Cancer Research. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Printed edition: |
| International Standard Book Number |
9783642114151 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-3-642-11416-8 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Item type |
E-Book |
