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| 003 - CONTROL NUMBER IDENTIFIER |
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OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20140310150243.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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111018s2012 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9783642216497 |
|
978-3-642-21649-7 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
QH573-671 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
571.6 |
| Edition number |
23 |
| 264 #1 - |
|---|
| -- |
Berlin, Heidelberg : |
| -- |
Springer Berlin Heidelberg : |
| -- |
Imprint: Springer, |
| -- |
2012. |
| 912 ## - |
|---|
| -- |
ZDB-2-SBL |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Denman, Robert B. |
| Relator term |
editor. |
| 245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Title |
Modeling Fragile X Syndrome |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc |
edited by Robert B. Denman. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XII, 392 p. |
| Other physical details |
online resource. |
| 440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE |
|---|
| Title |
Results and Problems in Cell Differentiation, |
| International Standard Serial Number |
0080-1844 ; |
| Volume number/sequential designation |
54 |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Introduction: Reminiscing on Models and Modeling -- Probing Astrocyte Function in Fragile X Syndrome -- Neural Stem Cells -- Fragile X Mental Retardation Protein (FMRP) and the Spinal Sensory System -- The role of the postsynaptic density in the pathology of the fragile X syndrome -- Behavior in a Drosophila model of Fragile X -- Molecular and Genetic Analysis of the Drosophila Model of Fragile X Syndrome -- Fragile X Mental Retardation Protein and Stem Cells -- Manipulating the Fragile Mental Retardation Proteins in the frog -- Exploring the zebra finch Taeniopygia guttata as a novel animal model for the speech-language deficit of fragile X syndrome -- Neuroendocrine alterations in the fragile X mouse -- Taking STEPs forward to understanding Fragile X Syndrome -- Fmr-1 as an offspring genetic and a maternal environmental factor in neurodevelopmental disease -- Mouse Models of the Fragile X Premutation and the Fragile X Associated Tremor/Ataxia Syndrome -- Clinical Aspects of the Fragile X Syndrome -- Fragile X Syndrome: A Psychiatric Perspective -- Fragile X Syndrome and Targeted Treatment Trials -- The Fragile X-associated Tremor Ataxia Syndrome -- Vignettes: Models in Absentia. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
The present book is an in-depth synopsis of recent advances in the fragile X field. The fragile X syndrome (FXS) is the most common form of inherited mental retardation, and the molecular-genetic basis of this syndrome has been the subject of extensive experimental scrutiny over the last two decades. This book covers the spectrum of current FXS research, ranging from Drosophila model systems via mouse models to clinical and psychiatric aspects. The volume also provides updates on FXS-related diseases such as the fragile X-associated tremor/ataxia syndrome. Significant progress in recent years, as highlighted here by some of the most eminent researchers in the field, are grounds for optimism that successful therapeutical approaches may be feasible in the not too distant future. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Life sciences. |
|
|---|
| Topical term or geographic name as entry element |
Human genetics. |
|
|---|
| Topical term or geographic name as entry element |
Gene therapy. |
|
|---|
| Topical term or geographic name as entry element |
Medicine. |
|
|---|
| Topical term or geographic name as entry element |
Cytology. |
|
|---|
| Topical term or geographic name as entry element |
Stem cells. |
|
|---|
| Topical term or geographic name as entry element |
Neurobiology. |
|
|---|
| Topical term or geographic name as entry element |
Life Sciences. |
|
|---|
| Topical term or geographic name as entry element |
Cell Biology. |
|
|---|
| Topical term or geographic name as entry element |
Human Genetics. |
|
|---|
| Topical term or geographic name as entry element |
Molecular Medicine. |
|
|---|
| Topical term or geographic name as entry element |
Neurobiology. |
|
|---|
| Topical term or geographic name as entry element |
Stem Cells. |
|
|---|
| Topical term or geographic name as entry element |
Gene Therapy. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Printed edition: |
| International Standard Book Number |
9783642216480 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-3-642-21649-7 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Item type |
E-Book |
