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OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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20140310150245.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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131209s2013 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783642402326 |
|
978-3-642-40232-6 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
QR46 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
616.9041 |
| Edition number |
23 |
| 264 #1 - |
|---|
| -- |
Berlin, Heidelberg : |
| -- |
Springer Berlin Heidelberg : |
| -- |
Imprint: Springer, |
| -- |
2013. |
| 912 ## - |
|---|
| -- |
ZDB-2-SBL |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Pieters, Jean. |
| Relator term |
editor. |
| 245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Title |
Pathogenesis of Mycobacterium tuberculosis and its Interaction with the Host Organism |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc |
edited by Jean Pieters, John D. McKinney. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
VIII, 245 p. 22 illus., 11 illus. in color. |
| Other physical details |
online resource. |
| 440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE |
|---|
| Title |
Current Topics in Microbiology and Immunology, |
| International Standard Serial Number |
0070-217X ; |
| Volume number/sequential designation |
374 |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Genetic Diversity in Mycobacterium tuberculosis -- DNA Metabolism in Mycobacterial Pathogenesis -- Molecular Biology of Drug Resistance in Mycobacterium tuberculosis -- Antimicrobial Efflux Pumps and Mycobacterium tuberculosis Drug Tolerance: Evolutionary Considerations -- Getting Across the Cell Envelope: Mycobacterial Protein Secretion -- A Single-Cell Perspective on Non-Growing but Metabolically Active (NGMA) Bacteria -- Mycobacterium tuberculosis Metabolism and Host Interaction: Mysteries and Paradoxes -- Surviving the Macrophage: Tools and Tricks Employed by Mycobacterium tuberculosis -- Host-Pathogen Interactions During Mycobacterium tuberculosis Infections. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
Mycobacterium tuberculosis is one of the most notorious pathogens on earth, causing the death of approximately 1.5 million people annually. A major problem in the fight against tuberculosis is the emergence of strains that have acquired resistance to all available antibiotics. One key to the success of M. tuberculosis as a pathogen is its ability to circumvent host immune responses at different levels. This is not only a result of the special makeup of M. tuberculosis in terms of genetic diversity and DNA metabolism and its possession of specialized secretion systems, but also of its ability to hijack the host’s innate immune defence mechanisms. In this volume, researchers from different disciplines provide a topical overview of the diverse mechanisms that contribute to the virulence of M. tuberculosis, ranging from their genetic, metabolic and molecular makeup, as well as the complex strategies these bacteria utilize to escape immune destruction within infected hosts. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Medicine. |
|
|---|
| Topical term or geographic name as entry element |
Immunology. |
|
|---|
| Topical term or geographic name as entry element |
Microbiology. |
|
|---|
| Topical term or geographic name as entry element |
Drug interactions. |
|
|---|
| Topical term or geographic name as entry element |
Microbial genetics. |
|
|---|
| Topical term or geographic name as entry element |
Biomedicine. |
|
|---|
| Topical term or geographic name as entry element |
Medical Microbiology. |
|
|---|
| Topical term or geographic name as entry element |
Immunology. |
|
|---|
| Topical term or geographic name as entry element |
Molecular Medicine. |
|
|---|
| Topical term or geographic name as entry element |
Drug Resistance. |
|
|---|
| Topical term or geographic name as entry element |
Microbial Genetics and Genomics. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
McKinney, John D. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Printed edition: |
| International Standard Book Number |
9783642402319 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-3-642-40232-6 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Item type |
E-Book |
