000 -LEADER |
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03358nam a22004335i 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
OSt |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20140310150246.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
fixed length control field |
cr nn 008mamaa |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
121213s2012 au | s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9783709112069 |
|
978-3-7091-1206-9 |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
QH506 |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
611.01816 |
Edition number |
23 |
264 #1 - |
-- |
Vienna : |
-- |
Springer Vienna : |
-- |
Imprint: Springer, |
-- |
2012. |
912 ## - |
-- |
ZDB-2-SBL |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Sebestik, Jaroslav. |
Relator term |
author. |
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
Title |
Biomedical Applications of Peptide-, Glyco- and Glycopeptide Dendrimers, and Analogous Dendrimeric Structures |
Medium |
[electronic resource] / |
Statement of responsibility, etc |
by Jaroslav Sebestik, Milan Reinis, Jan Jezek. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
XVII, 238 p. 29 illus., 19 illus. in color. |
Other physical details |
online resource. |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
Introduction -- Chemistry and struture to dendrimers: Definition of terms and nomenclature -- Sugar code (glyco code) -- Classes of peptide-, glyco, and glycopeptide dendrimers -- The dendritic state and dendritic effects -- Synthesis of dendrimers: convergent and divergent approaches -- Purification and characterization of dendrimers -- Dendrimeric libraries -- Dendrimers in catalysis.-Dendrimers and their biological and therapeutic applications: Dendrimers and solubility -- Biocompability and toxicity of dendrimers -- Dendrimers in nanoscience and nanotechnology -- Dendrimers in drug delivery -- Dendrimers in gene delivery.-Dendrimers and bacteria -- Dendrimers and viruses -- Dendrimers and parasites -- Cancer -- Diagnostics, lectin detection and cell-cell interactions -- Dendrimers as biosensors and imaging tools -- Dendrimers regulating in intracellular signaling pathways -- Vaccines and immunomodulation -- Dendrimers in neurodegenerative diseases -- Conclusions and persperctives. . |
520 ## - SUMMARY, ETC. |
Summary, etc |
Dendrimers are repeatedly branched and roughly spherical large molecules. They can be used in various medical applications, such as anticancer polymeric nanomedicines and nanocarriers, gene carriers and vectors in gene delivery, contrast agents for molecular imaging and vaccines against infectious diseases and cancer. The highly branched, multivalent nature and molecular architecture of dendrimers make them ideal tools for a variety of tissue engineering applications. This book describes different categories of dendrimers, their biomedical and physico-chemical applications as well as convergent and divergent syntheses, click chemistry and ligation strategies. It is a rich source of information for researchers in biochemistry and pharmacology working on drug development as well as for organic chemists who are engaged in synthesis of dendrimers. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name as entry element |
Medicine. |
|
Topical term or geographic name as entry element |
Pharmaceutical technology. |
|
Topical term or geographic name as entry element |
Biomedicine. |
|
Topical term or geographic name as entry element |
Molecular Medicine. |
|
Topical term or geographic name as entry element |
Biomedicine general. |
|
Topical term or geographic name as entry element |
Pharmaceutical Sciences/Technology. |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Reinis, Milan. |
Relator term |
author. |
|
Personal name |
Jezek, Jan. |
Relator term |
author. |
710 2# - ADDED ENTRY--CORPORATE NAME |
Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
773 0# - HOST ITEM ENTRY |
Title |
Springer eBooks |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Display text |
Printed edition: |
International Standard Book Number |
9783709112052 |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-3-7091-1206-9 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
|
Item type |
E-Book |