| 000 -LEADER |
|---|
| fixed length control field |
03833nam a22004935i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20140310150247.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
|---|
| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
100316s2010 ne | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9789048133031 |
|
978-90-481-3303-1 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
R-RZ |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
610 |
| Edition number |
23 |
| 264 #1 - |
|---|
| -- |
Dordrecht : |
| -- |
Springer Netherlands, |
| -- |
2010. |
| 912 ## - |
|---|
| -- |
ZDB-2-SBL |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Bunce, Chris M. |
| Relator term |
editor. |
| 245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Title |
Nuclear Receptors |
| Medium |
[electronic resource] : |
| Remainder of title |
Current Concepts and Future Challenges / |
| Statement of responsibility, etc |
edited by Chris M. Bunce, Moray J. Campbell. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XII, 365p. |
| Other physical details |
online resource. |
| 440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE |
|---|
| Title |
Proteins and Cell Regulation ; |
| Volume number/sequential designation |
8 |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Nuclear Receptors an Introductory Overview -- What does Evolution Teach us about Nuclear Receptors? -- Functions of Nuclear Receptors in Insect Development -- The Glucocorticoid Receptor -- Estrogen Receptors: Their Actions and Functional Roles in Health and Disease -- Androgen Receptor -- Thyroid Hormone Receptors -- The Vitamin D Receptor (NR1I1) -- Retinoic Acid Receptors -- PPARs: Important Regulators in Metabolism and Inflammation -- Xenobiotic Receptors CAR and PXR -- Fxr -- Physiological Functions of TR2 and TR4 Orphan Nuclear Receptor -- Nuclear Receptors and ATP Dependent Chromatin Remodeling: A Complex Story -- Non-Genomic Action of Sex Steroid Hormones -- Ligand Regulation and Nuclear Receptor Action -- New Insights to Nuclear Receptor Gene Regulation from Analysis of their Response Elements in Target Genes -- Systems Biology: Towards Realistic and Useful Models of Molecular Networks. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
In 1890 a case of myxedema was treated in Lisbon by the implantation of a sheep thyroid gland with the immediate improvement in the patient’s condition. A few years later, medications for the then ill-explained condition of the menopause included tablets made from cow ovaries. In the first quarter of the 20th century the identification of vitamin D, and its sunlight driven production in skin, paved the way to the elimination of rickets as a major medical problem. Twenty years or so later, Sir Vincent Wigglesworth established the endocrine basis of developmental moulting in insects, arguably the most commonly performed animal behaviour on Planet Earth. A paradigm that would unify these disparate observations arose between 1985 and 1987 beginning with the identification of the glucocorticoid receptor and the nuclear receptor super-family. What follows is a timely and positive manifestation of the capacity, productivity and value of international human scientific endeavour. Based on intrigue, lively competition and cooperation a global effort has rapidly fostered a school of biology with widespread ramifications for the understanding of metazoan animals, the human condition and the state of the planet. This book is the first this century to try and capture the spirit of this endeavour, to depict where the field is now and to identify some of the challenges and opportunities for the future. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Medicine. |
|
|---|
| Topical term or geographic name as entry element |
Endocrinology. |
|
|---|
| Topical term or geographic name as entry element |
Oncology. |
|
|---|
| Topical term or geographic name as entry element |
Biochemistry. |
|
|---|
| Topical term or geographic name as entry element |
Cytology. |
|
|---|
| Topical term or geographic name as entry element |
Biomedicine. |
|
|---|
| Topical term or geographic name as entry element |
Biomedicine general. |
|
|---|
| Topical term or geographic name as entry element |
Cell Biology. |
|
|---|
| Topical term or geographic name as entry element |
Endocrinology. |
|
|---|
| Topical term or geographic name as entry element |
Animal Biochemistry. |
|
|---|
| Topical term or geographic name as entry element |
Oncology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Campbell, Moray J. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Printed edition: |
| International Standard Book Number |
9789048133024 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-90-481-3303-1 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Item type |
E-Book |
