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003 - CONTROL NUMBER IDENTIFIER |
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005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20140310150247.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
fixed length control field |
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008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9789048134359 |
|
978-90-481-3435-9 |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
QH506 |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
611.01816 |
Edition number |
23 |
264 #1 - |
-- |
Dordrecht : |
-- |
Springer Netherlands, |
-- |
2010. |
912 ## - |
-- |
ZDB-2-SBL |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Gerasimovskaya, Evgenia. |
Relator term |
editor. |
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
Title |
Extracellular ATP and Adenosine as Regulators of Endothelial Cell Function |
Medium |
[electronic resource] : |
Remainder of title |
Implications for Health and Disease / |
Statement of responsibility, etc |
edited by Evgenia Gerasimovskaya, Elzbieta Kaczmarek. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
XI, 300p. |
Other physical details |
online resource. |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
Purinergic and Pyriminergic Activation of the Endothelium in Regulation of Tissue Perfusion -- Nucleotides and Novel Signaling Pathways in Endothelial Cells: Possible Roles in Angiogenesis, Endothelial Dysfunction and Diabetes Mellitus -- Extracellular Purines in Endothelial Cell Barrier Regulation -- The P2Y2 Nucleotide Receptor in Vascular Inflammation and Angiogenesis -- Role of Purine-Converting Ecto-Enzymes in Angiogenic Phenotype of Pulmonary Artery Adventitial Vasa Vasorum Endothelial Cells of Chronically Hypoxic Calves -- Stimulation of Wound Revascularization by Adenosine Receptor Activation -- Hypoxia-Inducible Factors and Adenosine Signaling in Vascular Growth -- Regulated Extracellular Nucleotide Metabolism and Function at the Mucosa -- Cell Surface ATP Synthase: A Potential Target for Anti-Angiogenic Therapy -- ATP Release Via Connexin Hemichannels Controls Intercellular Propagation of Ca2+ Waves in Corneal Endothelial Cells -- Pregnancy Induced Reprogramming of Endothelial Function in Response to ATP: Evidence for Post Receptor Ca2+ Signaling Plasticity -- Purinergic Signalling in Pancreatic Islet Endothelial Cells. |
520 ## - SUMMARY, ETC. |
Summary, etc |
Extracellular purines and pyrimidines (ATP, ADP, UTP and adenosine) are released into the extracellular milieu in response to a variety of stress conditions and act as important regulators of vascular homeostasis. This new book is uniquely focused on the signaling actions of extracellular purines in endothelial cells and the crucial role of extracellular purines in regulation of angiogenesis, vascular tone, cell permeability, wound healing, inflammation and cell-to-cell communication. This book examines the responses of endothelial cells, originating from various tissues (such as cornea, pancreas and uterus), to extracellular nucleotides and adenosine under physiological and pathological conditions, i.e. pregnancy, hypoxia, hypertension, inflammation and diabetes. In the book’s 12 chapters, the role of purinergic signaling in endothelium-dependent tissue perfusion, regulation of endothelial barrier function, and angiogenesis are discussed. The mechanisms of ATP release and its role in intercellular communication are also presented. In addition, the book provides the most up to date mechanisms of extracellular nucleotide metabolism by purine-converting ecto-enzymes and their contribution to purinergic signaling in endothelial cells originating from various vascular beds. This book is a valuable resource for biomedical research scientists, clinical scientists, graduate students and health science professionals interested in the mechanisms of extracellular purine function in endothelial cells under physiologic and pathologic conditions. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name as entry element |
Medicine. |
|
Topical term or geographic name as entry element |
Biochemistry. |
|
Topical term or geographic name as entry element |
Pathology. |
|
Topical term or geographic name as entry element |
Cytokines. |
|
Topical term or geographic name as entry element |
Cytology. |
|
Topical term or geographic name as entry element |
Biomedicine. |
|
Topical term or geographic name as entry element |
Molecular Medicine. |
|
Topical term or geographic name as entry element |
Medical Biochemistry. |
|
Topical term or geographic name as entry element |
Cytokines and Growth Factors. |
|
Topical term or geographic name as entry element |
Cell Physiology. |
|
Topical term or geographic name as entry element |
Pathology. |
|
Topical term or geographic name as entry element |
Biomedicine general. |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Kaczmarek, Elzbieta. |
Relator term |
editor. |
710 2# - ADDED ENTRY--CORPORATE NAME |
Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
773 0# - HOST ITEM ENTRY |
Title |
Springer eBooks |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Display text |
Printed edition: |
International Standard Book Number |
9789048134342 |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-90-481-3435-9 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
|
Item type |
E-Book |