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Quality Issues in Clinical Genetic Services (Record no. 18452)

000 -LEADER
fixed length control field 06612nam a22004695i 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140310150248.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 100628s2010 ne | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9789048139194
978-90-481-3919-4
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number R108
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 610.724
Edition number 23
264 #1 -
-- Dordrecht :
-- Springer Netherlands,
-- 2010.
912 ## -
-- ZDB-2-SBL
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Kristoffersson, Ulf.
Relator term editor.
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE
Title Quality Issues in Clinical Genetic Services
Medium [electronic resource] /
Statement of responsibility, etc edited by Ulf Kristoffersson, Jörg Schmidtke, J. J. Cassiman.
300 ## - PHYSICAL DESCRIPTION
Extent XXII, 400p.
Other physical details online resource.
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Improving Quality and Harmonization of Standards in Clinical Genetic Services in Europe: The EuroGentest Network of Excellence -- The CanGèneTest Pan-Canadian Research Consortium on Genetic Laboratory Services -- Regulating Genetic Testing: The Relevance of Appropriate Definitions -- Genetic Diseases as Rare Diseases: A European Policy View -- European Regulatory Issues Related to Quality in Provision of Genetic Service -- The European IVD Directive and Genetic Testing -- Quality Issues in Genetics Services in the United Kingdom -- The Primary Care Perspective of Quality in Clinical Genetics Service – United Kingdom as an Example -- Regulation of Genetic Testing/Service in Canada -- Quality Issues in Clinical Genetic Services in Australia -- Clinical Genetic Testing and Services – The US Perspective -- US Oversight and Regulation of Genetic Testing -- Regulatory Issues in Clinical and Laboratory Genetics in Developing Countries; Examples from Latin America -- Assuring Quality When Establishing Medical Genetic Services in Middle- and Low-Income Nations -- Clinical Validity and Utility of Genetic Testing in Heritable Disorders -- Clinical Validity and Utility of Genetic Testing in Common Multifactorial Diseases -- The Quality of Genetic Screening: An Integral Approach -- The Use of Principles in Allocating Scarce Health Care Resources for Genetic Tests -- Outcome Measures in Clinical Genetics Services -- Direct to Consumer Testing -- Competency Based Core Curriculum for Training Specialists in Clinical Genetics -- Ensuring Education and Quality in the Practice of Health Professionals (Non-medical) Working in Genetic Services -- Quality Issues in Clinical Genetic Services: Ethical Aspects -- Democratic Expert Influence Through Bioethical Advisory Committees? The Case of PGD Legislation in Sweden -- Quality Issues in Clinical Genetic Services; Regulatory Issues and International Conventions -- IPR Issues and High Quality Genetic Testing -- Quality Issues in the Evaluation and Regulation of Genetic Testing Services: A Public Health Approach -- Quality Management Systems and Accreditation -- External Quality Assessment in Molecular Genetic Testing -- Quality Issues in Molecular Genetic Testing -- Quality in Cytogenetics -- Fluorescence In Situ Hybridization (FISH) – Quality Issues in Molecular Cytogenetics -- Quality Issues in Biochemical Genetic Testing -- Emerging Technologies, Need for Quality Assessment -- Genetic Counselling in Rare Diseases -- Genetic Counselling for Late-Onset Disorders -- Genetic Counselling for Common Diseases, Cancer Susceptibility as Paradigm -- Genetic Counselling in Disorders of Low Penetrance -- Patient Perspectives on Genetic Testing.
520 ## - SUMMARY, ETC.
Summary, etc Initially genetic disorders were all considered as rare diseases. At present, in the mid of 2009, the OMIM catalogue contains information on more than 12 000 entries of which about 2500 are available for clinical testing based on the identification of the responsible gene defect. However, altogether it has been estimated that about 8 percent of a population in the economically developed countries will during their lifetime suffer from a disease mainly as the result of their genetic constitution. Adding to that, it is estimated that all diseases have a genetic component, which will determine who will be at a higher than average risk for a certain disorder. Further it is postulated that in the near future, this genetic profiling could become useful in selecting an appropriate therapy adapted to the genetic constitution of the person. Thus, genetic disorders are not rare. Measuring quality of health care related processes became an issue in the 1990s, mainly in laboratory medicine, but also for hospitals and other health care systems. In many countries national authorities started to implement recommendations, guidelines or legal procedures regulating quality of health care delivery. In laboratory medicine, in parallel, the use of accreditation as a method assuring high quality standards in testing came in use. With the increasing possibilities of performing molecular genetic testing, genetic laboratories needed to become involved in this process. As many genetic disorders are rare, most laboratories worldwide offered analysis for a specific set of disorders, and, therefore, very early on a transborder flow of samples occurred. While international quality criteria (ISO) have been in existence for a number of years, the regulation of quality issues still may differ between countries. Based on their personal experience in the varying fields of quality research and clinical implementation of quality criteria in genetic services the authors of this book share their experience and give examples of the implementation of quality issues in national quality systems worldwide. This book, which is the result of the effort of many persons, is destined, to aid laboratory managers and counsellors, health care managers and other stakeholders in national or international health care service to improve the services to the benefit of patients with suspected genetic disorders.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
Topical term or geographic name as entry element Human genetics.
Topical term or geographic name as entry element Medical laboratories.
Topical term or geographic name as entry element Medical Education.
Topical term or geographic name as entry element Biomedicine.
Topical term or geographic name as entry element Laboratory Medicine.
Topical term or geographic name as entry element Medicine/Public Health, general.
Topical term or geographic name as entry element Human Genetics.
Topical term or geographic name as entry element Medical Education.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Schmidtke, Jörg.
Relator term editor.
Personal name Cassiman, J. J.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9789048139187
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-90-481-3919-4
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Item type E-Book
Copies
Price effective from Permanent location Date last seen Not for loan Date acquired Source of classification or shelving scheme Koha item type Damaged status Lost status Withdrawn status Current location Full call number
2014-04-08AUM Main Library2014-04-08 2014-04-08 E-Book   AUM Main Library610.724
Languages: 
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العربية