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003 - CONTROL NUMBER IDENTIFIER |
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005 - DATE AND TIME OF LATEST TRANSACTION |
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20140310150248.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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100812s2010 ne | s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9789048190607 |
|
978-90-481-9060-7 |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
R-RZ |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
610 |
Edition number |
23 |
264 #1 - |
-- |
Dordrecht : |
-- |
Springer Netherlands : |
-- |
Imprint: Springer, |
-- |
2010. |
912 ## - |
-- |
ZDB-2-SBL |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Leung, Po Sing. |
Relator term |
author. |
245 14 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
Title |
The Renin-Angiotensin System: Current Research Progress in The Pancreas |
Medium |
[electronic resource] : |
Remainder of title |
The RAS in the Pancreas / |
Statement of responsibility, etc |
by Po Sing Leung. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
XVI, 208 p. |
Other physical details |
online resource. |
440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE |
Title |
Advances in Experimental Medicine and Biology, |
International Standard Serial Number |
0065-2598 ; |
Volume number/sequential designation |
690 |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
The Pancreas -- Overview of the Pancreas -- Physiology of the Pancreas -- Common Pancreatic Disease -- The Renin-Angiotensin System (RAS) -- Circulating RAS -- Local RAS -- Pancreatic RAS -- Research Progress Of The Ras In Pancreas -- Basic Techniques for Pancreatic Research -- Current Research of the RAS in Diabetes Mellitus -- Current Research Concerning the RAS in Pancreatic Stem Cells -- Current Research of the RAS in Pancreatitis and Pancreatic Cancer. |
520 ## - SUMMARY, ETC. |
Summary, etc |
The human pancreas has vital roles in the regulation of glucose homeostasis and digestion and its dysfunction leads to pancreatic disease as diabetes and pancreatitis. Recent researches have highlighted the novel roles of a local renin-angiotensin system (RAS) in the pancreas and its clinical relevances; its inapprporiate activation leads to pancreatic endocrine and exocrine disease, notably type 2 diabetes. As such, manipulation of the overactive RAS may improve pancreatic islet cell function, cell mass and insulin sensitivity, as well as enhancing the growth and differentiation of pancreatic stem cells. Blockade of the RAS may be protective against pancreatitis and pancreatic cancer. The research outcome of current progress on the RAS in the pancreas should provide an alternative approach to preventing and treating, as well as curing pancreatic disease. This book discusses the progress of research on the renin-angiotensin system in the pancreas from the science to the bedside, providing a timely review of this expanding area. It consists of ten interrelated chapters covering subjects as: – Structure, physiology and disease of the pancreas – Biochemistry and physiology of the pancreatic renin-angiotensin system – RAS in diabetes, stem cells and pancreatitis This book is of special value to basic and clinical scientists, clinicians, graduate students, as well as novices in this field. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name as entry element |
Medicine. |
|
Topical term or geographic name as entry element |
Human physiology. |
|
Topical term or geographic name as entry element |
Diabetes. |
|
Topical term or geographic name as entry element |
Gastroenterology. |
|
Topical term or geographic name as entry element |
Biomedicine. |
|
Topical term or geographic name as entry element |
Biomedicine general. |
|
Topical term or geographic name as entry element |
Human Physiology. |
|
Topical term or geographic name as entry element |
Diabetes. |
|
Topical term or geographic name as entry element |
Gastroenterology. |
710 2# - ADDED ENTRY--CORPORATE NAME |
Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
773 0# - HOST ITEM ENTRY |
Title |
Springer eBooks |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Display text |
Printed edition: |
International Standard Book Number |
9789048190591 |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-90-481-9060-7 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
|
Item type |
E-Book |