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Mortalin Biology: Life, Stress and Death (Record no. 18766)

000 -LEADER
fixed length control field 04767nam a22004815i 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140310150252.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 120323s2012 ne | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9789400730274
978-94-007-3027-4
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number QH506
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 611.01816
Edition number 23
264 #1 -
-- Dordrecht :
-- Springer Netherlands :
-- Imprint: Springer,
-- 2012.
912 ## -
-- ZDB-2-SBL
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Kaul, Sunil C.
Relator term editor.
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE
Title Mortalin Biology: Life, Stress and Death
Medium [electronic resource] /
Statement of responsibility, etc edited by Sunil C. Kaul, Renu Wadhwa.
300 ## - PHYSICAL DESCRIPTION
Extent XIV, 339p. 71 illus., 48 illus. in color.
Other physical details online resource.
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Contributors -- Foreword -- Preface -- Section 1: Structure and Function of Mortalin.-  1. Birth of Mortalin: Multiple Names, Niches and Functions Connecting Stress, Senescence and Cancer.-  2. Mortalin’s Machinery.-  3. The Role of Mortalin in Iron Homeostasis .-  4. Functional Characteristics of Mortalin.- Section 2:  Mortalin in Evolution2 Deocaris.-  5.  Mortalin and Drosophila DmHsp22: Two Mitochondrial Chaperones Regulating Aging and Carcinogenesis .-  6. Mortalin in Invertebrates and The Induction of Apoptosis by Wild-Type p53 Following Defeat of Mortalin-Based Cytoplasmic Sequestration in Cancerous Clam Hemocytes  .-  7. Mortalin and Stem Cells: A Study from Planarians.-  Section 3: Mortalin in Health and Disease.-  8. Mortalin in Cell Protection from Immune Attack .-  9. Mortalin in Neurological Diseases.-  10. Loss of Mortalin Function in Parkinson’s Disease – Supporting the Mitochondrial Pathway of Neurodegeneration.-  11. Hsp75/mortalin and Protection from Ischemic Brain Injury -- 12. Catecholamine Regulated Protein (CRP40), A Splice Variant of Mortalin-2: Functional Role in CNS Disorders.-  13. Chaperonopathies: Diseases in Which Mortalin and Other Hsp-Chaperones Play a Role in Etiology and Pathogenesis.-  Section 4:  Mortalin and Cancer.-  14. The Many Faces of Mortalin and Tid1.-  15. Mortalin: A Positive Regulator of Centrosome Duplication and Amplification.-  16. Mortalin Expression in Normal and Neoplastic Tissues .-  17. Mortalin - p53 Interaction as A Target for Liver Cancer Therapy.-  18. Mortalin Targeting Gadgets for Cancer Therapy -- Section 5:  Mortalin Based Technologies.-  19. Cell Internalizing Anti-Mortalin Antibody for Generation of Illuminating MSCs for Long-Term in vitro and in vivo Tracking.-  20. Mortalin Staining Pattern as A Reporter for Cell Based Anti-Cancer Drug Screening.-  21. Cell Internalizing Anti-Mortalin Antibody as a Nanocarrier.
520 ## - SUMMARY, ETC.
Summary, etc The phrase “Life, stress and death” connects three terms, but is there a biological basis for that? Are there molecules that are essential to/or mediate these phenomena? This contributory volume “Mortalin Biology: Life, Stress and Death” is a remarkable compilation of the research outcomes on the stress protein mortalin, a member of heat shock 70 family of proteins. The book is unique as it describes mortalin playing essential role in life, stress response and death either from cancer, when it becomes hyperactive or from neuro-degeneration, when it becomes hypoactive. The book provides up-to-date knowledge on mortalin with respect to its discovery, structure, evolutionary conservation, function and signal transduction in different organisms in a simple, but most comprehensive way, that besides offering an enjoyable and in-depth reading, prompts the reader to ask further questions to explore this protein with new ideas, approaches and experiments. Twenty-one chapters by the world leaders on the specific areas of mortalin research throw light on its multi-functionality, potentials for biotechnology, diagnostics and therapeutic values. Avenues of mortalin biology, yet unexplored, hold immense promises for future, and reading this volume provides an easy, enthusiastic and energetic head-on start.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
Topical term or geographic name as entry element Oncology.
Topical term or geographic name as entry element Medical genetics.
Topical term or geographic name as entry element Neurosciences.
Topical term or geographic name as entry element Nanotechnology.
Topical term or geographic name as entry element Biomedicine.
Topical term or geographic name as entry element Molecular Medicine.
Topical term or geographic name as entry element Gene Function.
Topical term or geographic name as entry element Cancer Research.
Topical term or geographic name as entry element Neurosciences.
Topical term or geographic name as entry element Nanotechnology.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Wadhwa, Renu.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9789400730267
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-94-007-3027-4
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Item type E-Book
Copies
Price effective from Permanent location Date last seen Not for loan Date acquired Source of classification or shelving scheme Koha item type Damaged status Lost status Withdrawn status Current location Full call number
2014-04-08AUM Main Library2014-04-08 2014-04-08 E-Book   AUM Main Library611.01816