000 -LEADER |
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02531nam a22004815i 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
OSt |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20140310150252.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
fixed length control field |
cr nn 008mamaa |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
120404s2012 ne | s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9789400742161 |
|
978-94-007-4216-1 |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
RC261-271 |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
614.5999 |
Edition number |
23 |
264 #1 - |
-- |
Dordrecht : |
-- |
Springer Netherlands, |
-- |
2012. |
912 ## - |
-- |
ZDB-2-SBL |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Berencsi III, György. |
Relator term |
editor. |
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
Title |
Maternal Fetal Transmission of Human Viruses and their Influence on Tumorigenesis |
Medium |
[electronic resource] / |
Statement of responsibility, etc |
edited by György Berencsi III. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
VIII, 464p. 18 illus. |
Other physical details |
online resource. |
520 ## - SUMMARY, ETC. |
Summary, etc |
The human foetus is separated from the maternal blood by the syncytiotrophoblast induced by endogeneous human retrovirus-encoded proteins. This barrier is a highly developed one, which suppors apical-basolateral transport of maternal idiotype and anti-idiotype IgG, IgG-virus complexes. The selective maternal-fetal transport of epitope- and paratope-bearing entities can influence the developping fetal immune system during pregnancy. The bidirectional maternal-fetal transfer of cells are of even more importance during pregnancy. Maternal cells with latent viruses transport viruses without impairment of fetal development. Cells with premaligant and malignant genetic transformation are also transported to the fetus. Fetal and neonatal tumours are initiated by such cells in spite of the antitumour potential of fetal organism. On the contary, the fetal cells repair maternal tissue injouries and survive in the organisms of the recipients for decades. These possess new consequences for the neonatal immunity and organ transplatation surgery. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name as entry element |
Medicine. |
|
Topical term or geographic name as entry element |
Oncology. |
|
Topical term or geographic name as entry element |
Immunology. |
|
Topical term or geographic name as entry element |
Medical virology. |
|
Topical term or geographic name as entry element |
Pediatrics. |
|
Topical term or geographic name as entry element |
Epidemiology. |
|
Topical term or geographic name as entry element |
Biomedicine. |
|
Topical term or geographic name as entry element |
Cancer Research. |
|
Topical term or geographic name as entry element |
Virology. |
|
Topical term or geographic name as entry element |
Immunology. |
|
Topical term or geographic name as entry element |
Oncology. |
|
Topical term or geographic name as entry element |
Pediatrics. |
|
Topical term or geographic name as entry element |
Epidemiology. |
710 2# - ADDED ENTRY--CORPORATE NAME |
Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
773 0# - HOST ITEM ENTRY |
Title |
Springer eBooks |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Display text |
Printed edition: |
International Standard Book Number |
9789400742154 |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-94-007-4216-1 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
|
Item type |
E-Book |