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003 - CONTROL NUMBER IDENTIFIER |
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005 - DATE AND TIME OF LATEST TRANSACTION |
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20140310150254.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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130228s2013 ne | s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9789400760288 |
|
978-94-007-6028-8 |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
R-RZ |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
610 |
Edition number |
23 |
264 #1 - |
-- |
Dordrecht : |
-- |
Springer Netherlands : |
-- |
Imprint: Springer, |
-- |
2013. |
912 ## - |
-- |
ZDB-2-SBL |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Martin, Tracey A. |
Relator term |
editor. |
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
Title |
Tight Junctions in Cancer Metastasis |
Medium |
[electronic resource] / |
Statement of responsibility, etc |
edited by Tracey A. Martin, Wen G. Jiang. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
VIII, 313 p. 46 illus., 40 illus. in color. |
Other physical details |
online resource. |
440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE |
Title |
Cancer Metastasis - Biology and Treatment, |
International Standard Serial Number |
1568-2102 ; |
Volume number/sequential designation |
19 |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
Preface -- The molecular aspects of Tight junctions -- The distribution of tight junctions and junctional proteins in the body -- Methodologies in investigation tight junctions -- Vascular permeability and drug delivery -- Tight junctions, BBB and brain metastasis -- Tight junctions and bladder cancer metastasis -- Tight Junctions and colorectal cancer therapies -- Tight junctions in breast cancer -- Regulation of tight junctions for therapeutic advantages -- Overcoming tight junctional permeability in cerebral metastasis -- CL-5 and cancer metastasis -- Intracellular signalling in TJ and AJ -- ROCK and TJ -- Index. |
520 ## - SUMMARY, ETC. |
Summary, etc |
There has been a dramatic increase in knowledge of tight junctions in the past decade. The molecular structure of tight junctions, cellular functions and the pathophysiological roles of tight junctions are becoming clear. Of the most important functions, the role of the cellular structure in cancer spread and drug delivery are increasingly realised. It is now clear that there are fundamental changes to tight junctions during the process of cancer development. Tight junctions are also critical to the metastatic process of cancer cells. The cellular structure is also crucial in drug therapies, namely, the permeability and bioavailability of the drugs, penetration of barriers such as the blood brain barrier. This current volume aims to summarise the current knowledge of tight junctions, their role in cancer and cancer metastasis and is of interest to scientists and clinicians. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name as entry element |
Medicine. |
|
Topical term or geographic name as entry element |
Oncology. |
|
Topical term or geographic name as entry element |
Cytology. |
|
Topical term or geographic name as entry element |
Cell membranes. |
|
Topical term or geographic name as entry element |
Biomedicine. |
|
Topical term or geographic name as entry element |
Biomedicine general. |
|
Topical term or geographic name as entry element |
Cancer Research. |
|
Topical term or geographic name as entry element |
Oncology. |
|
Topical term or geographic name as entry element |
Cell Biology. |
|
Topical term or geographic name as entry element |
Membrane Biology. |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Jiang, Wen G. |
Relator term |
editor. |
710 2# - ADDED ENTRY--CORPORATE NAME |
Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
773 0# - HOST ITEM ENTRY |
Title |
Springer eBooks |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Display text |
Printed edition: |
International Standard Book Number |
9789400760271 |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-94-007-6028-8 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
|
Item type |
E-Book |