| 000 -LEADER |
|---|
| fixed length control field |
04062nam a22004575i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20140310150254.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
|---|
| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
130809s2013 ne | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9789400762114 |
|
978-94-007-6211-4 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
RC261-271 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
614.5999 |
| Edition number |
23 |
| 264 #1 - |
|---|
| -- |
Dordrecht : |
| -- |
Springer Netherlands : |
| -- |
Imprint: Springer, |
| -- |
2013. |
| 912 ## - |
|---|
| -- |
ZDB-2-SBL |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Resende, Rodrigo R. |
| Relator term |
editor. |
| 245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Title |
Trends in Stem Cell Proliferation and Cancer Research |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc |
edited by Rodrigo R. Resende, Henning Ulrich. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XVIII, 661 p. 77 illus., 58 illus. in color. |
| Other physical details |
online resource. |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Part I Molecular bases for stem and cancer cells proliferation -- An introduction to proliferation and migration of stem cells and cancer -- the role of cell adhesions, cell junctions and extracellular matrix in normal development and carcinogenesis -- The embryonic rest hypothesis of cancer development: 150 years later -- Are calcium channels more important than calcium influx for cell proliferation ?- Role of calcium signaling in stem cells and cancer cells proliferation -- |Formation and function of lipid droplets in inflammation and cancer -- The role of sphingolipids in modulating pluripotency of stem cells -- Part II Signaling pathways to cancer cells fate -- Signaling pathways of cbl-b and its role on peripheral t cell tolerance -- Bh3-only proteins in cancer and apoptosis -- Signaling pathways of mta family proteins as regulators of cancer progression and metastasis -- Signalling pathways of β-catenin/jnk on carcinogenesis.- The regulation of the jnk cascade and programmed cell death by nf-κb: mechanisms and functions -- Part III Uncontrolled physiology process guiding to cancer cells -- Migration, metastasis and more: the role of chemokines in the proliferation, spreading and metastasis of tumors -- Autophagy, cell death, and cancer -- the duality of stem cells – double edged sword in tumour evolution and treatment -- Glioblastoma stem cells and implications for chemoresistance -- The tumor microenvironment as a transient niche: a modulator of epigenetic states and stem cell functions -- Tumor-associated neutrophils (tans) -- Microrna control of apoptotic programs in cancer -- Part IV Therapeutic strategies for anticancer treatment -- Markers of cancer stem cells and their functions -- Cancer cell dormancy: potential therapeutic targets to eradicate cancer cells within the niche -- Modulating apoptosis in cancer therapy with ultrasound and high intensity nanosecond electric pulses -- Targeting cell cycle for anticancer treatment and neuroprotection. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
The book will discuss the molecular mechanisms of cancer diseases, stem cell proliferation and transformation into cancer cells beyond the physiological processes that occur in normal stem cell biology. Some of the key oncogenic events in cancer and their signaling pathways that regulate cell division cycle progression will be described considering prospects for using such knowledge in advanced cancer therapy. Each chapter shall provide an invaluable resource for information on the most current advances in the field, with discussion of controversial issues and areas of emerging importance |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Medicine. |
|
|---|
| Topical term or geographic name as entry element |
Oncology. |
|
|---|
| Topical term or geographic name as entry element |
Cytology. |
|
|---|
| Topical term or geographic name as entry element |
Stem cells. |
|
|---|
| Topical term or geographic name as entry element |
Biomedicine. |
|
|---|
| Topical term or geographic name as entry element |
Cancer Research. |
|
|---|
| Topical term or geographic name as entry element |
Stem Cells. |
|
|---|
| Topical term or geographic name as entry element |
Cell Biology. |
|
|---|
| Topical term or geographic name as entry element |
Biomedicine general. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Ulrich, Henning. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Printed edition: |
| International Standard Book Number |
9789400762107 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-94-007-6211-4 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Item type |
E-Book |
