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03236nam a22004095i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20140310150641.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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110617s2011 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9781441994615 |
|
978-1-4419-9461-5 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
RC681-688.2 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
616.12 |
| Edition number |
23 |
| 264 #1 - |
|---|
| -- |
Boston, MA : |
| -- |
Springer US, |
| -- |
2011. |
| 912 ## - |
|---|
| -- |
ZDB-2-SME |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Marín-García, José. |
| Relator term |
author. |
| 245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Title |
Signaling in the Heart |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc |
by José Marín-García. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XX, 507p. 96 illus., 90 illus. in color. |
| Other physical details |
online resource. |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Tools to Study Signaling -- Cell-cycle Signaling, Epigenetic and Nuclear Function -- Signaling in the Endothelium -- Rapid Signaling Pathways -- Growth Factors Signaling Pathways -- Ion Channels Signaling -- Lipids Signaling -- Heart Mitochondria: A Receiver and Integrator of Signals -- Signaling Pathways in Cardiovascular Development -- Signaling in Congenital Heart Disease -- Signaling in the Aging Heart -- Signaling in Endomyocarditis -- Signaling Pathways in Hypertension -- Gene Expression and Signaling Pathways in Myocardial Ischemia -- Signaling in Hypertrophy and Heart Failure -- Signaling in Diabetes and Metabolic Syndrome -- Dysrhythmias/Channelopathies and Signaling Pathways -- Signaling in Atherosclerosis -- Stem Cells Signaling Pathways -- Cardioprotection and Signaling Pathways -- Targeting Specific Pathways -- Future Frontiers in Cardiovascular Signaling. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology. The heart is both a transmitter and dynamic receptor of a variety of intracellular and extracellular stimuli, playing a critical role of an integrator of diverse signaling mechanisms. Alterations in signaling pathways are contributing factors in the development and progression of a broad spectrum of diseases, ranging from dysrhythmias and atherosclerosis to hypertension and the metabolic syndrome. Targeting specific components of these signaling pathways has been shown to be effective in preclinical studies with significant therapeutic impact. This book brings together current knowledge in cardiovascular cell signal transduction mechanisms, advances in novel therapeutic approaches to improve cardiac function, and discussion of future directions. Presented from a post-genomic perspective, this exciting book introduces important new ideas in cardiovascular systems biology. It is an invaluable reference for cardiology researchers and practitioners. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Medicine. |
|
|---|
| Topical term or geographic name as entry element |
Cardiology. |
|
|---|
| Topical term or geographic name as entry element |
Biochemistry. |
|
|---|
| Topical term or geographic name as entry element |
Medicine & Public Health. |
|
|---|
| Topical term or geographic name as entry element |
Cardiology. |
|
|---|
| Topical term or geographic name as entry element |
Medical Biochemistry. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Printed edition: |
| International Standard Book Number |
9781441994608 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-4419-9461-5 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Item type |
E-Book |
