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Visual Dysfunction in Diabetes (Record no. 19759)

000 -LEADER
fixed length control field 05963nam a22004695i 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140310150647.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 111215s2012 xxu| s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781607611509
978-1-60761-150-9
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RE1-994
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 617.7
Edition number 23
264 #1 -
-- New York, NY :
-- Springer New York,
-- 2012.
912 ## -
-- ZDB-2-SME
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Tombran-Tink, Joyce.
Relator term editor.
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE
Title Visual Dysfunction in Diabetes
Medium [electronic resource] :
Remainder of title The Science of Patient Impairment and Health Care /
Statement of responsibility, etc edited by Joyce Tombran-Tink, Colin J. Barnstable, Thomas W. Gardner.
300 ## - PHYSICAL DESCRIPTION
Extent XV, 379p. 72 illus., 51 illus. in color.
Other physical details online resource.
440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE
Title Ophthalmology Research
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Introduction -- Diabetic Retinopathy – what we know, don’t know, and need to know.- A Patient’s viewpoint.- What patients with diabetes see—and don’t see: subjective and objective visual function changes.- How do I know I have diabetic retinopathy – a clinician’s view?.- Epidemiology & Economics.- Correlation between the presence and severity of diabetic retinopathy in families with diabetes.- Increasing public awareness of the diabetes endemic.- Nutrition and diabetes.- Diabetic retinopathy screening – progress and complications.- Measurements of retinal blood flow, vascular leakage, and oxygenation.- Optical imaging - Confocal microscopy to detect retinal vasculature.- Structural imaging – OCT.- Functional imaging - ERG.- Clinical phenotypes (reclassification).- Vascular changes.- Neuronal changes.- Inflammatory changes.- Other Ocular Complications of Diabetes.- New insights in the pathogenesis of diabetic retinopathy using a proteomic approach – Retina.- Vitreous proteomics.- Genomics.- Genome-wide linkage analyses to identify Loci for diabetic retinopathy.- Risk Factors.- Diabetic retinopathy correlates with increased incidence of cardiovascular events.- Pregnancy and rate of progression of diabetic retinopathy.- Molecular Mechanisms that Could Trigger Visual Dysfunction in Diabetes -- Introduction.- Inflammation in the early pathogenesis of diabetic retinopathy —beauty and beast.- Oxidative stress and diabetic retinopathy.- Glucose induced cellular signaling in diabetic retinopathy.- The AGE/RAGE axis in early diabetic retinopathy.- Proteases and the retinal vasculature (and maybe the whole retina!).- IGFBP3 and retinal vessel growth.- PEDF, VEGF, CTGF review.- A decrease in the expression of somatostatin is an early event in diabetic retinopathy.- Connective tissue and connective tissue growth factor in diabetic retinopathy.- Molecular regulation of endothelial cell tight junctions and the blood retinal barrier.- Pericytes and diabetic retinopathy.- Leukostasis.- Adhesion molecules (ICAM-1 and VCAM-1) and diabetic retinopathy in type 2 diabetes.- Azurocidin as a Permeability Factor in the Retina.- Retinal arteriolar hemodynamic response to a combined isocapnic hyperoxia and glucose -- Provocation in early sight-threatening diabetic retinopathy.- Urinary 8-hydroxydeoxyguanosine (8-OHdG) levels in diabetic retinopathy patients.- Tyrosine nitration in the molecular mechanisms of diabetic retinopathy.
520 ## - SUMMARY, ETC.
Summary, etc An exciting contribution to the field, Visual Dysfunction in Diabetes: The Science of Patient Impairment and Improvement is designed with two overriding objectives: to help readers understand the impact of vision impairment in people living daily with diabetes rather than considering diabetic retinopathy solely as a medical problem, and to explore what we know and don't know about the ways diabetes affect the eye.  With the plethora of new information being generated, there are still a series of fundamental questions that must be addressed if effective treatments for diabetic retinopathy are to be found and applied.  Developed by a renowned group of authorities, Visual Dysfunction in Diabetes: The Science of Patient Impairment and Improvement offers responses and context for a range of questions, such as: do metabolic factors beyond glucose contribute to vision-threatening diabetic retinopathy? If so, how do these lead to vision impairment?  Is diabetic retinopathy a response to systemic metabolic abnormalities or are there unique ocular problems related to insulin resistance? What is the relationship between the neural, vascular, and inflammatory abnormalities in diabetic retinopathy? Do they represent a pathological cascade induced sequentially or simultaneous responses to one or more metabolic perturbations?  The authors note that if we do not address these types of questions, it is possible that the long process of developing new therapeutics will target only one arm of the pathology and leave the retina open to damaging consequences of the others. State-of-the-art, comprehensive, and an invaluable addition the research and clinical literature, Visual Dysfunction in Diabetes: The Science of Patient Impairment and Improvement offers guidance and a significant step toward new scientific approaches that can lessen the devastating vision impairment associated with diabetes.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
Topical term or geographic name as entry element Neurosciences.
Topical term or geographic name as entry element Endocrinology.
Topical term or geographic name as entry element Ophthalmology.
Topical term or geographic name as entry element Medicine & Public Health.
Topical term or geographic name as entry element Ophthalmology.
Topical term or geographic name as entry element Endocrinology.
Topical term or geographic name as entry element Neurosciences.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Barnstable, Colin J.
Relator term editor.
Personal name Gardner, Thomas W.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9781607611493
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-1-60761-150-9
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Item type E-Book
Copies
Price effective from Permanent location Date last seen Not for loan Date acquired Source of classification or shelving scheme Koha item type Damaged status Lost status Withdrawn status Current location Full call number
2014-04-07AUM Main Library2014-04-07 2014-04-07 E-Book   AUM Main Library617.7
Languages: 
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