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OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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20140310150647.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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111201s2012 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9781607614333 |
|
978-1-60761-433-3 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
RB1-214 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
616.07 |
| Edition number |
23 |
| 264 #1 - |
|---|
| -- |
New York, NY : |
| -- |
Springer New York, |
| -- |
2012. |
| 912 ## - |
|---|
| -- |
ZDB-2-SME |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Murphy, Michael J. |
| Relator term |
editor. |
| 245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Title |
Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc |
edited by Michael J. Murphy. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XIV, 322p. 29 illus., 24 illus. in color. |
| Other physical details |
online resource. |
| 440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE |
|---|
| Title |
Current Clinical Pathology |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Introduction to Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma -- Diagnostic and Prognostic Biomarkers in Melanoma: Current State of Play -- Molecular Pathogenesis of Melanoma: Established and Novel Pathways -- Staging of Melanoma -- Clinical and Histopathological Parameters in Melanoma -- Genetic/Epigenetic Biomarkers: Distinction of Melanoma from Other Melanocytic Neoplasms -- mRNA Biomarkers in Melanoma -- Epigenetic Biomarkers in Melanoma -- microRNA Biomarkers in Melanoma -- MicroRNAs as Biomarkers and Therapeutic Targets in Melanoma -- Mitochondrial DNA Biomarkers in Melanoma -- Tissue-Based Protein Biomarkers in Melanoma: Immunohistochemistry: (A) Diagnosis -- Tissue-Based Protein Biomarkers in Melanoma: Immunohistochemistry: (B) Prognostication -- Tissue-Based Protein Biomarkers in Melanoma: Mass Spectrometry-Based Strategies -- Serological Biomarkers in Melanoma -- Molecular Markers of Lymph Node Disease in Melanoma -- Melanoma Cell Propagation: Cancer Stem Cell, Clonal Evolution and Interconversion Models of Tumorigenicity -- Surgical Management of Melanoma: Concept of Field Cancerization and Molecular Evaluation of Tissue Margins -- Chemotherapy for Melanoma -- Molecular-Targeted Therapy for Melanoma -- Anti-Angiogenesis Therapy for Melanoma -- Immunological Biomarkers and Immunotherapy for Melanoma -- Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma: An Overview. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
This book describes both the technologies used in the discovery of melanoma biomarkers and the clinical application of these biomarkers for diagnosis and staging of disease, determination of prognosis, treatment planning, monitoring of response to therapy, identification of novel therapeutic targets and drug development. A broad range of biomarkers (DNA/chromosomal, mRNA, microRNA, mitochondrial DNA, epigenetic and protein) is outlined. As therapies for melanoma become increasingly more target specific, the identification, validation and use of biomarkers will invariably play a greater role in the management of patients with this disease. Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma is an essential resource for oncologists, dermatologists, dermatopathologists, general pathologists with an interest in melanoma, and melanoma researchers. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Medicine. |
|
|---|
| Topical term or geographic name as entry element |
Dermatology. |
|
|---|
| Topical term or geographic name as entry element |
Oncology. |
|
|---|
| Topical term or geographic name as entry element |
Pathology. |
|
|---|
| Topical term or geographic name as entry element |
Medicine & Public Health. |
|
|---|
| Topical term or geographic name as entry element |
Pathology. |
|
|---|
| Topical term or geographic name as entry element |
Oncology. |
|
|---|
| Topical term or geographic name as entry element |
Dermatology. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Printed edition: |
| International Standard Book Number |
9781607614326 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-60761-433-3 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Item type |
E-Book |
