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003 - CONTROL NUMBER IDENTIFIER |
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005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20140310150648.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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110302s2011 xxu| s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9781617379956 |
|
978-1-61737-995-6 |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
RC261-271 |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
614.5999 |
Edition number |
23 |
264 #1 - |
-- |
Totowa, NJ : |
-- |
Humana Press, |
-- |
2011. |
912 ## - |
-- |
ZDB-2-SME |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Penning, Trevor M. |
Relator term |
editor. |
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
Title |
Chemical Carcinogenesis |
Medium |
[electronic resource] / |
Statement of responsibility, etc |
edited by Trevor M. Penning. |
250 ## - EDITION STATEMENT |
Edition statement |
1. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
XVI, 440 p. |
Other physical details |
online resource. |
440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE |
Title |
Current Cancer Research |
520 ## - SUMMARY, ETC. |
Summary, etc |
This monograph provides a contemporary account of advances in chemical carcinogenesis. It promotes the view that it is alteration of the DNA by endogenous and exogenous carcinogens that ultimately leads to sporadic mutations which are a root cause of many human cancers. It deals with the metabolic activation of common classes of chemical carcinogens (tobacco carcinogens, heterocyclic amines, polycyclic aromatic hydrocarbons) and their detoxication. It describes the DNA-adducts that ensue and their repair mechanisms. It covers advances in structural-biology that provide a glimpse of both the DNA-repair process and the by-pass of DNA-lesions and how this informs the mutational code. It also deals with the concepts of chemoprevention and biomarkers for biomonitoring human exposure. Many contemporary texts on the biology of cancer now focus almost exclusively on the molecular and cell biology of the disease and do not cover the initiating (DNA damaging events) of chemical carcinogenesis in depth. It is with this perceived gap-in knowledge that world experts in their particular fields have contributed to this monograph. This monograph will be an important reference re-source for students in training, postdoctoral scientists, and senior scientists knowledgeable in the field. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name as entry element |
Medicine. |
|
Topical term or geographic name as entry element |
Oncology. |
|
Topical term or geographic name as entry element |
Toxicology. |
|
Topical term or geographic name as entry element |
Biomedicine. |
|
Topical term or geographic name as entry element |
Cancer Research. |
|
Topical term or geographic name as entry element |
Pharmacology/Toxicology. |
710 2# - ADDED ENTRY--CORPORATE NAME |
Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
773 0# - HOST ITEM ENTRY |
Title |
Springer eBooks |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Display text |
Printed edition: |
International Standard Book Number |
9781617379949 |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-61737-995-6 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
|
Item type |
E-Book |