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04198nam a22004455i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20140310150652.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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121204s2013 fr | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9782817803432 |
|
978-2-8178-0343-2 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
RC648-665.2 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
616.4 |
| Edition number |
23 |
| 264 #1 - |
|---|
| -- |
Paris : |
| -- |
Springer Paris : |
| -- |
Imprint: Springer, |
| -- |
2013. |
| 912 ## - |
|---|
| -- |
ZDB-2-SME |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Bastard, Jean-Philippe. |
| Relator term |
editor. |
| 245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Title |
Physiology and Physiopathology of Adipose Tissue |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc |
edited by Jean-Philippe Bastard, Bruno Fève. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XIX, 437 p. 51 illus. in color. |
| Other physical details |
online resource. |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Foreword -- Part I: Adipose tissue development -- 1. Development of adipose cells -- 2. Emerging roles of cell cycle regulators in adipocyte metabolism -- 3. Angiogenesis in adipose tissue -- 4. Prospects for using adipose tissue in regenerative medicine -- 5. Brown adipose tissue: function and development -- 6. Histology of adipose tissue -- Part II: Adipose tissue metabolic functions -- 7. Glucose transport in white adipocyte -- 8. Mechanism of storage and synthesis of fatty acids and triglycerides in white adipocytes -- 9. Adipocyte lipid droplet physiology -- 10. Adipose tissue lipolysis -- 11. The adipose tissue: storage, source and target of pollutants -- Part III: Endocrine functions of adipocyte -- 12. Chatting between the brain and white adipose tissues -- 13. Adiponectin: an adipokine with multiple faces -- 14. Apelin metabolic functions -- 15. Up-to-date on novel “adipocrines” -- Part IV: Pathology of adipose tissue -- 16. Obesity: an evolving process -- 17. Obesity phenotypes : Measures to assess adipose tissue mass in humans -- 18. Animal models of obesity -- 19. Contribution of “omics” approaches to understand the pathophysiology of obesity -- 20. Adipose tissue inflammation in obesity -- 21. Impact of proinflammatory cytokines on adipocyte insulin signaling -- 22. Adaptive changes in human adipose tissue during weight gain -- 23. Differences between subcutaneous and visceral adipose tissues -- 24. Genetics of human obesities -- 25. Genetic and acquired lipodystrophic syndromes -- 26. Is adipose tissue a relevant therapeutic target of obesity?. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
The scientific advances in the physiology and pathophysiology of adipose tissue over the last two decades have been considerable. Today, the cellular and molecular mechanisms of adipogenesis are well known. In addition, adipose tissue is now recognized as a real endocrine organ that produces hormones such as the leptin acting to regulate food intake and energy balance in the central nervous system, a finding that has completely revolutionized the paradigm of energy homeostasis. Other adipokines have now been described and these molecules are taking on increasing importance in physiology and pathophysiology. Moreover, numerous works have shown that in obesity, but also in cases of lipodystophy, adipose tissue was the site of a local low-grade inflammation that involves immune cells such as macrophages and certain populations of lymphocytes. This new information is an important step in the pathophysiology of both obesity and related metabolic and cardiovascular complications. Finally, it is a unique and original work focusing on adipose tissue, covering biology and pathology by investigating aspects of molecular and cellular biology, general, metabolic, genetic and genomic biochemistry. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Medicine. |
|
|---|
| Topical term or geographic name as entry element |
Endocrinology. |
|
|---|
| Topical term or geographic name as entry element |
Metabolic diseases. |
|
|---|
| Topical term or geographic name as entry element |
Lipids. |
|
|---|
| Topical term or geographic name as entry element |
Medicine & Public Health. |
|
|---|
| Topical term or geographic name as entry element |
Endocrinology. |
|
|---|
| Topical term or geographic name as entry element |
Metabolic Diseases. |
|
|---|
| Topical term or geographic name as entry element |
Lipidology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Fève, Bruno. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Printed edition: |
| International Standard Book Number |
9782817803425 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-2-8178-0343-2 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Item type |
E-Book |
