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Antimicrobial Peptides and Innate Immunity (Record no. 20180)

000 -LEADER
fixed length control field 04126nam a22004815i 4500
003 - CONTROL NUMBER IDENTIFIER
control field OSt
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20140310150653.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 130131s2013 sz | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783034805414
978-3-0348-0541-4
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number QR180-189.5
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 616.079
Edition number 23
264 #1 -
-- Basel :
-- Springer Basel :
-- Imprint: Springer,
-- 2013.
912 ## -
-- ZDB-2-SME
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Hiemstra, Pieter S.
Relator term editor.
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE
Title Antimicrobial Peptides and Innate Immunity
Medium [electronic resource] /
Statement of responsibility, etc edited by Pieter S. Hiemstra, Sebastian A. J. Zaat.
300 ## - PHYSICAL DESCRIPTION
Extent XI, 384 p. 38 illus., 23 illus. in color.
Other physical details online resource.
440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE
Title Progress in Inflammation Research
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Evolution of Antimicrobial Peptides: a View From the Cystine Chapel -- Innate immunity in plants: the role of antimicrobial peptides -- Antimicrobial peptides produced by microorganisms -- LL-37: an immunomodulatory antimicrobial host defence peptide -- Wound Repair and Antimicrobial Peptides -- WAPing out pathogens and disease in the mucosa-roles for SLPI and trappin-2 -- Histatins: multifunctional salivary antimicrobial peptides -- Structure-function relationships of antimicrobial chemokines -- Mechanisms and Significance of Bacterial Resistance to Human Cationic Antimicrobial Peptides -- Antimicrobial peptides and inflammatory bowel disease -- Cystic Fibrosis and Defective Airway Innate Immunity -- Antimicrobial peptides in chronic obstructive pulmonary disease -- Host defense peptides: Immune modulation and antimicrobial activity in vivo -- Helping the host – induction of antimicrobial peptides as a novel therapeutic strategy against infections.
520 ## - SUMMARY, ETC.
Summary, etc Antimicrobial peptides have been the subject of intense research in the past decades, and are now considered as an essential part of the defense system in bacteria, plants, animals and humans. This book provides an update on these effector molecules of the innate immune system both for researchers who are already actively involved in the area, and for those with a general interest in the topic. The book starts with an overview of the evolution of cysteine-containing antimicrobial peptides (including defensins), and the role of these peptides in host defense in plants and micro-organisms. The realization that antimicrobial peptides also display functions distinct from their direct antimicrobial action is the focus of the next chapters, and puts these peptides center stage in immunity and wound repair.  Further chapters discuss the role of antimicrobial peptides in disease, by providing an overview of mechanisms in bacterial resistance to antimicrobial peptides and a discussion of their role in inflammatory bowel disease, cystic fibrosis lung disease and chronic obstructive pulmonary disease. Finally, the book shows how knowledge of the function of antimicrobial peptides and their regulation can be used to design new therapies for inflammatory and infectious disorders. This is a very important area of research because of the increase in resistance of micro-organisms to conventional antibiotics. Therefore the use of synthetic or recombinant peptides, or agents that stimulate the endogenous production of antimicrobial peptides, provides an attractive alternative for conventional antibiotics.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
Topical term or geographic name as entry element Immunology.
Topical term or geographic name as entry element Microbiology.
Topical term or geographic name as entry element Emerging infectious diseases.
Topical term or geographic name as entry element Biochemistry.
Topical term or geographic name as entry element Biomedicine.
Topical term or geographic name as entry element Immunology.
Topical term or geographic name as entry element Infectious Diseases.
Topical term or geographic name as entry element Biochemistry, general.
Topical term or geographic name as entry element Medical Microbiology.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Zaat, Sebastian A. J.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9783034805407
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://dx.doi.org/10.1007/978-3-0348-0541-4
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Item type E-Book
Copies
Price effective from Permanent location Date last seen Not for loan Date acquired Source of classification or shelving scheme Koha item type Damaged status Lost status Withdrawn status Current location Full call number
2014-04-07AUM Main Library2014-04-07 2014-04-07 E-Book   AUM Main Library616.079