| 000 -LEADER |
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| fixed length control field |
03865nam a22005175i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20140310150654.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
|---|
| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
100301s2010 gw | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9783642001505 |
|
978-3-642-00150-5 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
RD1-811 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
617 |
| Edition number |
23 |
| 264 #1 - |
|---|
| -- |
Berlin, Heidelberg : |
| -- |
Springer Berlin Heidelberg, |
| -- |
2010. |
| 912 ## - |
|---|
| -- |
ZDB-2-SME |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Dufour, Jean-Francois. |
| Relator term |
editor. |
| 245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Title |
Signaling Pathways in Liver Diseases |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc |
edited by Jean-Francois Dufour, Pierre-Alain Clavien. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
VIII, 578 p. 41 illus., 22 illus. in color. |
| Other physical details |
online resource. |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
The Cell Types and the Matrix -- Hepatocytes -- Signaling Pathways in Biliary Epithelial Cells -- Stellate Cells -- Signaling Pathways in Liver Diseases Kupffer Cells -- Hepatic Sinusoidal Endothelial Cells -- Extracellular Matrix -- Platelets: A New Cell Type in Liver Physiology -- Immune Cell Communication and Signaling Systems in Liver Disease -- The Pathways -- Toll-Like Receptors -- TNF/TNF Receptors -- Fas/FasL -- Interferon Signaling -- NF-?B -- JNKs in liver diseases -- Insulin Pathway -- Role of PKB/Akt in Liver Diseases -- Targeting mTOR Signaling Pathways in Liver Disease -- AMP-Activated Protein Kinase in Liver -- ER Stress Signaling in Hepatic Injury -- PPAR?, A Key Regulator of Hepatic Energy Homeostasis in Health and Disease -- Bile Acids and Their Receptors -- Signaling Pathways in Liver Diseases: PXR and CAR -- p53 -- The MYC Network and Cancer -- The WNT/?-Catenin Pathway -- Sonic Hedgehog Pathway -- Hypoxia-Inducible Factor-1 Signaling System -- VEGF Signaling -- Apoptosis and Mitochondria -- Calcium Signaling -- HBV Signaling -- Hepatitis C Virus and Insulin Signaling -- MicroRNAs -- Hepatic Clocks. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
Signaling Pathways in Liver Diseases, 2nd edition focuses on signaling pathways which are particularly important in liver diseases. Recent progress brought hepatology to new frontiers. The increasing frequency of surgery on steatotic and cirrhotic liver obliges liver surgeons and hepatologists to understand the molecular mechanisms at play in these situations and how they can be influenced. Better comprehension of the cellular mechanisms participating in liver regeneration, hepato-cellular apoptosis and ischemia/reperfusion inquiry is mirrored by a dramatic increase in complexity. The number and scope of publications is intimidating and difficult for busy individuals to extract a coherent framework. This book will serve as a source of information facilitating the reading of the literature and the planning of trials. Translational medicine implies knowledge of the molecular targets for novel therapeutic strategies. It will furthermore stimulate more research and lead to better exchange between the laboratory, the clinical ward and the operation room. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Medicine. |
|
|---|
| Topical term or geographic name as entry element |
Internal medicine. |
|
|---|
| Topical term or geographic name as entry element |
Gastroenterology. |
|
|---|
| Topical term or geographic name as entry element |
Clinical medicine. |
|
|---|
| Topical term or geographic name as entry element |
Surgery. |
|
|---|
| Topical term or geographic name as entry element |
Endoscopic surgery. |
|
|---|
| Topical term or geographic name as entry element |
Transplantation of organs, tissues, etc. |
|
|---|
| Topical term or geographic name as entry element |
Medicine & Public Health. |
|
|---|
| Topical term or geographic name as entry element |
General Surgery. |
|
|---|
| Topical term or geographic name as entry element |
Hepatology. |
|
|---|
| Topical term or geographic name as entry element |
Gastroenterology. |
|
|---|
| Topical term or geographic name as entry element |
Internal Medicine. |
|
|---|
| Topical term or geographic name as entry element |
Minimally Invasive Surgery. |
|
|---|
| Topical term or geographic name as entry element |
Transplant Surgery. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Clavien, Pierre-Alain. |
| Relator term |
editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Printed edition: |
| International Standard Book Number |
9783642001499 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-3-642-00150-5 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Item type |
E-Book |
