| 000 -LEADER |
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03019nam a22004695i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20140310150702.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
120103s2012 ne | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9789400728493 |
|
978-94-007-2849-3 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
R-RZ |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
610 |
| Edition number |
23 |
| 264 #1 - |
|---|
| -- |
Dordrecht : |
| -- |
Springer Netherlands, |
| -- |
2012. |
| 912 ## - |
|---|
| -- |
ZDB-2-SME |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Prokop, Aleš. |
| Relator term |
author. |
| 245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Title |
Systems Biology in Biotech & Pharma |
| Medium |
[electronic resource] : |
| Remainder of title |
A Changing Paradigm / |
| Statement of responsibility, etc |
by Aleš Prokop, Seth Michelson. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XVIII, 127p. 16 illus. in color. |
| Other physical details |
online resource. |
| 440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE |
|---|
| Title |
SpringerBriefs in Pharmaceutical Science & Drug Development, |
| International Standard Serial Number |
1864-8118 ; |
| Volume number/sequential designation |
2 |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Abstract -- 1 Introduction: Discovery & Development - New Facet Of Industry, New Tools And Lead Optimization: 1.1 Scope And Content Of This Review -- 2 Discovery: Use Of Systems Biology For Identifying Targets -- 3 Integrative Systems Biology I - Biochemistry: Phase I Lead Discovery & Molecular Interactions -- 4 Integrative Systems Biology Ii - Molecular Biology: Phase 2 Lead Discovery & In Silico Screening -- 5. Discovery: Computational Systems Biology (Csb) In Health & And Disease I -- 6 Development: In Vivo Pharmacology - Systems Biology In Health & Disease Ii -- 7 Development: Pharmacokinetics – Systems Biology In Health & Disease Iii -- 8 Development: Multiscale Csb – Simulation Tools -- 9 Development: Drug Formulation & Delivery -- 10 Development: Preclinical Model Based Drug Development -- 11 Systems Biology: Impact On Pharma And Biotech -- 12 Acknowledgment -- 13 Bibliography. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
Systems Biology (SB) is a suite of technologies and methodologies that resulted, conceptually from the merging of two basic paradigms, reductionism and holism. It represents a combination of reductionist and holistic approaches to the relationships among the elements of a system, with the goal of identifying its emergent properties and defining, quantitatively, molecular, cellular, tissue, organ and whole body processes. One manifestation of SB is as a tool for hypothesis generation about a system that is typically too large and complex to understand by simple reasoning. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Medicine. |
|
|---|
| Topical term or geographic name as entry element |
Pharmaceutical technology. |
|
|---|
| Topical term or geographic name as entry element |
Biotechnology. |
|
|---|
| Topical term or geographic name as entry element |
Microbiology. |
|
|---|
| Topical term or geographic name as entry element |
Biomedicine. |
|
|---|
| Topical term or geographic name as entry element |
Biomedicine general. |
|
|---|
| Topical term or geographic name as entry element |
Biotechnology. |
|
|---|
| Topical term or geographic name as entry element |
Applied Microbiology. |
|
|---|
| Topical term or geographic name as entry element |
Pharmaceutical Sciences/Technology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Michelson, Seth. |
| Relator term |
author. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Printed edition: |
| International Standard Book Number |
9789400728486 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-94-007-2849-3 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Item type |
E-Book |
