| 000 -LEADER |
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| fixed length control field |
03858nam a22004095i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20140310151115.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
100715s2010 xxk| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9781849961042 |
|
978-1-84996-104-2 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
QH324.2-324.25 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
570.285 |
| Edition number |
23 |
| 264 #1 - |
|---|
| -- |
London : |
| -- |
Springer London, |
| -- |
2010. |
| 912 ## - |
|---|
| -- |
ZDB-2-SCS |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Axelson-Fisk, Marina. |
| Relator term |
author. |
| 245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Title |
Comparative Gene Finding |
| Medium |
[electronic resource] : |
| Remainder of title |
Models, Algorithms and Implementation / |
| Statement of responsibility, etc |
by Marina Axelson-Fisk. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XV, 304 p. |
| Other physical details |
online resource. |
| 440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE |
|---|
| Title |
Computational Biology, |
| International Standard Serial Number |
1568-2684 ; |
| Volume number/sequential designation |
11 |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Single Species Gene Finding -- Sequence Alignment -- Comparative Gene Finding -- Gene Structure Submodels -- Parameter Training -- Implementation of a Comparative Gene Finder. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
Comparative genomics is an emerging field, which is being fed by an explosion in the number of possible biological sequences. This has led to an immense demand for faster, more efficient and more robust computer algorithms to analyze this large amount of data. This unique text/reference describes the state of the art in computational gene finding, with a particular focus on comparative approaches. Providing both an overview of the various methods that are applied in the field, and a concise guide on how computational gene finders are built, the book covers a broad range of topics from probability theory, statistics, information theory, optimization theory and numerical analysis. The text assumes the reader has some background in bioinformatics, especially in mathematics and mathematical statistics. A basic knowledge of analysis, probability theory and random processes would also aid the reader. Topics and features: Describes how algorithms and sequence alignments can be combined to improve the accuracy of gene finding Introduces the basic biological terms and concepts in genetics, and provides an historical overview of algorithm development Explores the gene features most commonly captured by a computational gene model, and describes the most important sub-models used Discusses the algorithms most commonly used for single-species gene finding Investigates approaches to pairwise and multiple sequence alignments Explains the basics of parameter training, covering a number of the different parameter estimation and optimization techniques commonly used in gene finding Illustrates how to implement a comparative gene finder, explaining the different steps and various accuracy assessment measures used to debug and benchmark the software A useful text for postgraduate students, this book provides valuable insights and examples for researchers wishing to enter the field quickly. In addition to the specific focus on the algorithmic details surrounding computational gene finding, readers obtain an introduction to the fundamentals of computational biology and biological sequence analysis, as well as an overview of the important mathematical and statistical applications in bioinformatics. Dr. Marina Axelson-Fisk is an Associate Professor at the Department of Mathematical Sciences of Chalmers University of Technology, Gothenburg, Sweden. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Computer science. |
|
|---|
| Topical term or geographic name as entry element |
Bioinformatics. |
|
|---|
| Topical term or geographic name as entry element |
Computer Science. |
|
|---|
| Topical term or geographic name as entry element |
Computational Biology/Bioinformatics. |
|
|---|
| Topical term or geographic name as entry element |
Bioinformatics. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Printed edition: |
| International Standard Book Number |
9781849961035 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-84996-104-2 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Item type |
E-Book |
