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120928s2013 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9781461443704 |
|
978-1-4614-4370-4 |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
QH505 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
571.4 |
| Edition number |
23 |
| 264 #1 - |
|---|
| -- |
New York, NY : |
| -- |
Springer New York : |
| -- |
Imprint: Springer, |
| -- |
2013. |
| 912 ## - |
|---|
| -- |
ZDB-2-PHA |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Thiriet, Marc. |
| Relator term |
author. |
| 245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Title |
Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc |
by Marc Thiriet. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XV, 1064 p. 31 illus. |
| Other physical details |
online resource. |
| 440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE |
|---|
| Title |
Biomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems, |
| International Standard Serial Number |
2193-1682 ; |
| Volume number/sequential designation |
4 |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
1. Introduction -- 2. Signaling Lipids -- 3. Preamble to Cytoplasmic Protein Kinases -- 4. Cytoplasmic Protein Tyrosine Kinases -- 5. Cytoplasmic Protein Serine/Threonine Kinases -- 6. Dual-Specificity Protein Kinases -- 7. Mitogen-Activated Protein Kinase Module -- 8. Dual-Specificity Protein Kinases -- 9. Guanosine Triphosphatases and Their Regulators -- 10. Other Major Types of Signaling Mediators -- 11. Signaling Pathways -- 12. Conclusion -- References -- List of Currently Used Prefixes and Suffixes -- List of Aliases.-Complementary Lists of Notations -- Index. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to phenomenological models of nano- and microscopic events in a corrector scheme of regulated mechanisms when the vessel lumen caliber varies markedly. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. Volume 4 is devoted to major sets of intracellular mediators that transmit signals upon stimulation of cell-surface receptors. Activation of signaling effectors triggers the release of substances stored in cellular organelles and/or gene transcription and protein synthesis. Complex stages of cell signaling can be studied using proper mathematical models, once the role of each component is carefully handled. Volume 4 also reviews various categories of cytosolic and/or nuclear mediators and illustrates some major signal transduction pathways, such as NFkappaB axis, oxygen sensing, and mechanotransduction. Reviews signaling pathways in the regulation of circulatory and respiratory function Describes ion and molecular carriers and receptors Integrates biology, chemistry, and physics for a multidisciplinary understanding of physiological flows |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Physics. |
|
|---|
| Topical term or geographic name as entry element |
Cardiology. |
|
|---|
| Topical term or geographic name as entry element |
Biological models. |
|
|---|
| Topical term or geographic name as entry element |
Hydraulic engineering. |
|
|---|
| Topical term or geographic name as entry element |
Biomedical engineering. |
|
|---|
| Topical term or geographic name as entry element |
Physics. |
|
|---|
| Topical term or geographic name as entry element |
Biophysics and Biological Physics. |
|
|---|
| Topical term or geographic name as entry element |
Biomedical Engineering. |
|
|---|
| Topical term or geographic name as entry element |
Mathematical and Computational Biology. |
|
|---|
| Topical term or geographic name as entry element |
Systems Biology. |
|
|---|
| Topical term or geographic name as entry element |
Engineering Fluid Dynamics. |
|
|---|
| Topical term or geographic name as entry element |
Cardiology. |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY |
|---|
| Title |
Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Display text |
Printed edition: |
| International Standard Book Number |
9781461443698 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-1-4614-4370-4 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Item type |
E-Book |
