000 -LEADER |
fixed length control field |
03870nam a22005535i 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
OSt |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20140310153039.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
fixed length control field |
cr nn 008mamaa |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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130625s2013 gw | s |||| 0|eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9783642375552 |
|
978-3-642-37555-2 |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
QH345 |
|
Classification number |
QD415-436 |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
572 |
Edition number |
23 |
264 #1 - |
-- |
Berlin, Heidelberg : |
-- |
Springer Berlin Heidelberg : |
-- |
Imprint: Springer, |
-- |
2013. |
912 ## - |
-- |
ZDB-2-PHA |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Rahman, Masoud. |
Relator term |
author. |
245 10 - IMMEDIATE SOURCE OF ACQUISITION NOTE |
Title |
Protein-Nanoparticle Interactions |
Medium |
[electronic resource] : |
Remainder of title |
The Bio-Nano Interface / |
Statement of responsibility, etc |
by Masoud Rahman, Sophie Laurent, Nancy Tawil, L'Hocine Yahia, Morteza Mahmoudi. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
X, 84 p. 24 illus., 20 illus. in color. |
Other physical details |
online resource. |
440 1# - SERIES STATEMENT/ADDED ENTRY--TITLE |
Title |
Springer Series in Biophysics, |
International Standard Serial Number |
0932-2353 ; |
Volume number/sequential designation |
15 |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
The Biological Significance of ‘Nano’ interactions -- Nanoparticle and Protein Corona -- Protein Corona: Applications and Challenges -- Analytical Methods for Corona Evaluations. |
520 ## - SUMMARY, ETC. |
Summary, etc |
In recent years, the fabrication of nanomaterials and exploration of their properties have attracted the attention of various scientific disciplines such as biology, physics, chemistry, and engineering. Although nanoparticulate systems are of significant interest in various scientific and technological areas, there is little known about the safety of these nanoscale objects. It has now been established that the surfaces of nanoparticles are immediately covered by biomolecules (e.g. proteins, ions, and enzymes) upon their entrance into a biological medium. This interaction with the biological medium modulates the surface of the nanoparticles, conferring a “biological identity” to their surfaces (referred to as a “corona”), which determines the subsequent cellular/tissue responses. The new interface between the nanoparticles and the biological medium/proteins, called “bio-nano interface,” has been very rarely studied in detail to date, though the interest in this topic is rapidly growing. In this book, the importance of the physiochemical characteristics of nanoparticles for the properties of the protein corona is discussed in detail, followed by comprehensive descriptions of the methods for assessing the protein-nanoparticle interactions. The advantages and limitations of available corona evaluation methods (e.g. spectroscopy methods, mass spectrometry, nuclear magnetic resonance, electron microscopy, X-ray crystallography, and differential centrifugal sedimentation) are examined in detail, followed by a discussion of the possibilities for enhancing the current methods and a call for new techniques. Moreover, the advantages and disadvantages of protein-nanoparticle interaction phenomena are explored and discussed, with a focus on the biological impacts. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name as entry element |
Life sciences. |
|
Topical term or geographic name as entry element |
Toxicology. |
|
Topical term or geographic name as entry element |
Biochemistry. |
|
Topical term or geographic name as entry element |
RNA-ligand interactions. |
|
Topical term or geographic name as entry element |
Nanotechnology. |
|
Topical term or geographic name as entry element |
Life Sciences. |
|
Topical term or geographic name as entry element |
Biochemistry, general. |
|
Topical term or geographic name as entry element |
Protein-Ligand Interactions. |
|
Topical term or geographic name as entry element |
Pharmacology/Toxicology. |
|
Topical term or geographic name as entry element |
Biophysics and Biological Physics. |
|
Topical term or geographic name as entry element |
Nanoscale Science and Technology. |
|
Topical term or geographic name as entry element |
Nanotechnology. |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Laurent, Sophie. |
Relator term |
author. |
|
Personal name |
Tawil, Nancy. |
Relator term |
author. |
|
Personal name |
Yahia, L'Hocine. |
Relator term |
author. |
|
Personal name |
Mahmoudi, Morteza. |
Relator term |
author. |
710 2# - ADDED ENTRY--CORPORATE NAME |
Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
773 0# - HOST ITEM ENTRY |
Title |
Springer eBooks |
776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
Display text |
Printed edition: |
International Standard Book Number |
9783642375545 |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
http://dx.doi.org/10.1007/978-3-642-37555-2 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Source of classification or shelving scheme |
|
Item type |
E-Book |